Bioactivity and antibacterial properties of zinc-doped Ta₂O₅ nanorods on porous tantalum surface

Abstract

This paper focuses on the preparation of Zn2+-doped Ta2O5 nanorods on porous tantalum using the hydrothermal method. Porous tantalum is widely used in biomedical materials due to its excellent elastic modulus and biological activity. Porous tantalum has an elastic modulus close to that of human bone, and its large specific surface area is conducive to promoting cell adhesion. Zinc is an important component of human bone, which not only has spectral bactericidal properties, but also has no cytotoxicity. The purpose of this study is to provide a theoretical basis for the surface modification of porous tantalum and to determine the best surface modification method. The surface structure of the sample was characterized by XRD, XPS, SEM, TEM, and the Zn-doped Ta2O5 nanorods are characterized by antibacterial test, MTT test, ICP and other methods. The sample has good antibacterial properties and no cytotoxicity. The results of this study have potential implications for the development of new and improved biomedical materials.

Preparation, biological activity and antibacterial properties of tantalum surface-doped Ca2+/Zn2+ nanorods

“…NaRen et al [42] implemented ion exchange techniques to integrate Mg 2+ and Ca 2+ into the interlayers on titanium foil surfaces. This process, when compared to Na + -enriched titanate nanostructures, markedly increases protein adsorption due to the presence of divalent ions (Mg 2+ , Ca 2+ ), thus enhancing both the adsorption and differentiation capacities of rBMSCs [43]. Using various analytical methods such as ALP, EDX, FTIR and XRD, we demonstrated that calcium ions are superior to magnesium ions in promoting cell differentiation.…”