Bioactivity of CaO�SiO2-based glasses:in vitro evaluation

Influence of magnesia on the structure and properties of bioactive glasses

“…Magnesia has often been incorporated into bioactive glasses [18][19][20][21][22][23][24][25][26][27][28][29] It is suggested that the lack of structural understanding of magnesium within glasses has lead to the many conflicting views on its contribution with respect to bioactivity. MgO has been documented as decreasing apatite formation in SBF [26] but also, on the other hand, improving the early stages of mineralization [24] and contributing to an intimate contact with living tissue.…”

In Vitro Evaluation of Silicate Based Bioactive Glass

“…The simulated body fluid(SBF) can be used as physiological body fluid which mimics the human blood plasma. The ion concentrations of SBF is nearly equal to human blood plasma .This was successfully explained by kokubo et al [19]. Simulated body fluid is useful to conduct in vitro studies of bioactivity [20].…”

“…The first and foremost requirement of bioactive material is its compatibility [18]. This can be investigated by examining the formation of calcium phosphate rich layer on the surface of the bioactive glass when immersed in physiological body fluid [19]. The simulated body fluid(SBF) can be used as physiological body fluid which mimics the human blood plasma.…”

Crystallization and Mechanical Properties of (45s5-Ha) Biocomposite for Biomedical Implantation

“…The formation of silanol groups on material's surface which are essential for nucleation sites for HA formation is due to the simultaneous dissolution of silicates [30]. Once the apatite nuclei formed, they can grow spontaneously by uptaking calcium phosphate ions from the surrounding fluid [31]. For BC2, BC3 and BC4 composites, SEM at the high magnification indicates the presence of rich spherical shapes build upon each other to form a bonelike apatite layer for both composites especially BC4 composites.…”