Bioactivity of extracts from Alpinia zerumbet against sinusitis-causing bacterial pathogens

Costa, Grasiela Merícia; Suga, Rodrigo; Oliveira, Patrícia Luciana de; Silva, Fernando César; Magalhães, Paula Prazeres; Duarte, Lucienir Pains; Farias, Luiz M.

doi:10.5935/2446-4775.20150015

Cited by 6 publications

(6 citation statements)

References 15 publications

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“…Alpinia zerumbet is widely cultivated and distributed in tropical and semitropical areas, including Brazil (Thenmozhi et al 2011). It is a very popular medicinal plant in Brazil (Costa et al 2016). Alpinia zerumbet EO does not present cytotoxic or genotoxic action in vivo or in vitro (Oliveira 2008).…”

Section: Introductionmentioning

confidence: 99%

Effect of Alpinia zerumbet essential oil on the shelf life of tambaqui fillets during short-term refrigerator storage

et al. 2019

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We investigated the effect of Alpinia zerumbet essential oil on the quality and shelf life of tambaqui (Colossoma macropomum) fillets stored under refrigeration (10.0 ± 0.5 °C) for 14 days. The treatments were A. zerumbet essential oil at 0.75% v v-1 (AEO 0.75%), A. zerumbet essential oil at 1.5% v v-1 (AEO 1.5%) and a control (no essential oil). The sample quality and shelf life were determined by the total psychrotrophic count (TPC) and chemical parameters (pH, total volatile basic nitrogen, centesimal composition and thiobarbituric acid reactive substances - TBARS) at zero, seven and 14 days of storage time. The TPC decreased significantly (p < 0.05) with an A. zerumbetessential oil level of 1.5% until seven days of storage. The concentration of A. zerumbet essential oil at 0.75% resulted in lower pH, TBARS, and TVBN values in comparison with the other treatment and the control. Thus, A. zerumbet essential oil was efficient in extending the shelf life of refrigerated tambaqui fillets up to approximately seven days.

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Section: Introductionmentioning

confidence: 99%

Effect of Alpinia zerumbet essential oil on the shelf life of tambaqui fillets during short-term refrigerator storage

et al. 2019

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“…Furthermore, a broad spectrum of biological activities has been reported from different plant parts, including anti-nociceptive, antioxidant, hepatoprotective, cytotoxic, and antibacterial properties [8,10,11,12,13,14]. In addition, de Moura et al [15] reported promising anti-hypertensive activities of leaves from plants grown in Brazil.…”

Section: Introductionmentioning

confidence: 99%

HPLC-ESI-MS/MS Profiling of Polyphenolics of a Leaf Extract from Alpinia zerumbet (Zingiberaceae) and Its Anti-Inflammatory, Anti-Nociceptive, and Antipyretic Activities In Vivo

et al. 2018

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Reactive oxygen species (ROS) have been linked to several health conditions, among them inflammation. Natural antioxidants may attenuate this damage. Our study aimed to investigate the chemical composition of a methanol leaf extract from Alpinia zerumbet and its possible antioxidant, anti-inflammatory, anti-nociceptive, and antipyretic effects. Altogether, 37 compounds, representing benzoic and cinnamic acid derivatives and flavonoids (aglycones and glycosides), were characterized. The extract showed substantial in vitro antioxidant effects, and inhibited both cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) in vitro, with a higher selectivity towards COX-2. It also inhibited 5-lipoxygenase (LOX) activity in vitro with nearly double the potency of zileuton, a reference 5-lipoxygenase (LOX) inhibitor. The extract exhibited anti-inflammatory effects against carrageenan-induced rat hind paw edema, and suppressed leukocyte infiltration into the peritoneal cavity in carrageenan-treated mice. Furthermore, it possessed antipyretic effects against fever induced by subcutaneous injection of Brewer’s yeast in mice. Additionally, the extract demonstrated both central and peripheral anti-nociceptive effects in mice, as manifested by a decrease in the count of writhing, induced with acetic acid and an increase in the latency time in the hot plate test. These findings suggest that the leaf extract from Alpinia zerumbet could be a candidate for the development of a drug to treat inflammation and ROS related disorders.

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“…Alpinia spp. belongs to the ginger family, Zingiberaceae, and its extracts have been found to contain active compounds for therapeutic properties [99], including antioxidant, anti-inflammatory, and anti-microbial activities (Table 3) [100][101][102][103][104][105][106][107][108][109][110][111][112][113]. Effective against food contaminants that cause hepatotoxicity; possesses anti-inflammatory properties [112,113] 5,6-dehydrokawain (DK) and dihydro-5,6-dehydrokawain (DDK), found in the rhizomes and leaves of Alpinia zerumbet, exhibit antioxidant [101] characteristics and pro-foundly inhibit collagenase, elastase, hyaluronidase, and tyrosinase activity [100].…”

Section: Alpinia Spp Extracts and Their Active Compoundsmentioning

confidence: 99%

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

Valdez,

Shyur,

Wang

et al. 2023

Animals

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Necrotic enteritis is a devastating disease in chickens mainly caused by Clostridium perfringens—particularly, Net-B toxin-producing strains. In order to combat necrotic enteritis in broiler production, natural growth promoters, as well as anti-inflammatory and non-antibiotic remedies, were developed for anti-microbial resistance due to its status as a global pandemic. Herein, phytogenic ginger, wild marjoram, and cloves were reviewed as potential alternatives to antibiotics for their anti-microbial functions. These phytogenics contain active ingredients that efficiently modulate the immune response and improve intestinal morphology and overall growth performance, even under stress and infection conditions. Most of the beneficial effects can be attributed to their anti-inflammatory functions, primarily the inhibition of the NF-κB and MAPK pathways. Phytogenics and their active ingredients represent potential substitutes for antibiotic growth promoters, further serving as anti-microbial remedies in the treatment of birds with infections.

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Bioactivity of extracts from Alpinia zerumbet against sinusitis-causing bacterial pathogens

Cited by 6 publications

References 15 publications

Effect of Alpinia zerumbet essential oil on the shelf life of tambaqui fillets during short-term refrigerator storage

Effect of Alpinia zerumbet essential oil on the shelf life of tambaqui fillets during short-term refrigerator storage

HPLC-ESI-MS/MS Profiling of Polyphenolics of a Leaf Extract from Alpinia zerumbet (Zingiberaceae) and Its Anti-Inflammatory, Anti-Nociceptive, and Antipyretic Activities In Vivo

Phytogenics in Ginger, Origanum vulgare, and Syzygium aromaticum and Their Potential as a Feed Additive against Clostridium perfringens in Broiler Production

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