Bioactivity of mackerel peptides on obesity and insulin resistance, an in-vivo study

Hokmabadinazhad, Soheila Abachi; Songpadith, Jean-Philippe; Houde, Vanessa P.; Pilon, Geneviève; Fliss, Ismaı̈l; Marette, André; Bazinet, Laurent; Beaulieu, Lucie

doi:10.1016/j.fbio.2022.101641

Cited by 5 publications

(3 citation statements)

References 42 publications

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“…and algae (21,22). Marine peptides can also be derived from fish byproducts such as skin, viscera, scales, and heads (23,24), usually discarded into the environment, causing pollution.…”

Section: Introductionmentioning

confidence: 99%

The current research status and strategies employed to modify food-derived bioactive peptides

et al. 2022

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The ability of bioactive peptides to exert biological functions has mainly contributed to their exploitation. The exploitation and utilization of these peptides have grown tremendously over the past two decades. Food-derived peptides from sources such as plant, animal, and marine proteins and their byproducts constitute a more significant portion of the naturally-occurring peptides that have been documented. Due to their high specificity and biocompatibility, these peptides serve as a suitable alternative to pharmacological drugs for treating non-communicable diseases (such as cardiovascular diseases, obesity, and cancer). They are helpful as food preservatives, ingredients in functional foods, and dietary supplements in the food sector. Despite their unique features, the application of these peptides in the clinical and food sector is to some extent hindered by their inherent drawbacks such as toxicity, bitterness, instability, and susceptibility to enzymatic degradation in the gastrointestinal tract. Several strategies have been employed to eliminate or reduce the disadvantages of peptides, thus enhancing the peptide bioactivity and broadening the opportunities for their applications. This review article focuses on the current research status of various bioactive peptides and the strategies that have been implemented to overcome their disadvantages. It will also highlight future perspectives regarding the possible improvements to be made for the development of bioactive peptides with practical uses and their commercialization.

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“…and algae (21,22). Marine peptides can also be derived from fish byproducts such as skin, viscera, scales, and heads (23,24), usually discarded into the environment, causing pollution.…”

Section: Introductionmentioning

confidence: 99%

The current research status and strategies employed to modify food-derived bioactive peptides

et al. 2022

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“…The third step is the fractioning and purification of the peptides, which is carried out because most scientific reports indicate a greater biological activity of smaller peptides with variable sizes between 3 and 20 amino acids [18][19][20], although most sequences are between 2 and 4 amino acids long [16]. This stage is usually carried out using different techniques such as ultrafiltration membranes [21], electrodialysis [22], electrodialysis with ultrafiltration membrane [23,24] or different chromatographic techniques, among which size exclusion, ion exchange and high resolution liquid stand out [25]. Since the biological properties of the peptides are expressed by the peptide when it is incorporated to the protein [26], the analysis of the biological properties is carried out in several moments of the process.…”

Section: Introductionmentioning

confidence: 99%

Biological activities of peptides obtained by pepsin hydrolysis of fishery products

Castañeda‐Valbuena

Murcia

Fernández‐Lafuente

et al. 2022

Process Biochemistry

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“…Obesity, which is considered a systemic inflammatory condition, has become a global problem especially among residents of highly developed countries. It affects not only adults but also children and adolescents [ 3 ]. This multifactorial disease is associated with excessive body weight and adipose tissue deposition caused by consumption of too many calories relative to the demand.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Peptides Obtained from Legume Seeds as New Compounds in Metabolic Syndrome Prevention and Diet Therapy

Kiersnowska

Jakubczyk

2022

Foods

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Currently, food is regarded not only as a source of nutrients, vitamins, and minerals but also as a source of bioactive compounds that can play a significant role in the prevention and diet therapy of many diseases. Metabolic syndrome (MS) is a complex disorder defined as a set of interrelated factors that increase the risk of cardiovascular disease, atherosclerosis, type 2 diabetes, or dyslipidemia. MS affects not only adults but also children. Peptides are one of the compounds that exhibit a variety of bioactive properties. They are derived from food proteins, which are usually obtained through enzymatic hydrolysis or digestion in the digestive system. Legume seeds are a good source of bioactive peptides. In addition to their high protein content, they contain high levels of dietary fiber, vitamins, and minerals. The aim of this review is to present new bioactive peptides derived from legume seeds and showing inhibitory properties against MS. These compounds may find application in MS diet therapy or functional food production.

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Bioactivity of mackerel peptides on obesity and insulin resistance, an in-vivo study

Cited by 5 publications

References 42 publications

The current research status and strategies employed to modify food-derived bioactive peptides

The current research status and strategies employed to modify food-derived bioactive peptides

Biological activities of peptides obtained by pepsin hydrolysis of fishery products

Bioactive Peptides Obtained from Legume Seeds as New Compounds in Metabolic Syndrome Prevention and Diet Therapy

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