Bioactivity of Moschamindole from Centaurea moschata

Abstract

The antioxidant and antibacterial properties of moschamindole (1), an indole alkaloid isolated from the methanol extract of the seeds of Centaurea moschata, have been assessed. General toxicity of this compound has also been determined by the brine shrimp lethality bioassay.

Chrozophorin: a new acylated flavone glucoside from Chrozophora tinctoria (Euphorbiaceae)

“…The crude MeOH extract showed low levels of free radical scavenging activity (antioxidant activity) (RC 50 = 2.24 x 10 -1 mg/mL) in the DPPH assay (Kumarasamy et al, 2002;Takao et al, 1994). However, even this low level of activity was an indication of the presence of antioxidant compounds, which upon purifi cation from the crude extract could show more signifi cant activity.…”

“…Apigenin 7 -O-β-D-[6-(3,4-dihydroxybenzoyl) Takao et al (1994) was adopted with suitable modifi cations to our particular circumstance (Kumarasamy et al, 2002). DPPH (4 mg) was dissolved in MeOH (50 mL) to obtain a concentration of 80 μg/mL.…”

Essential oil composition and isolation of freeradical-scavenging phenolic glycosides from the aerial parts of Ajuga chamaepitys growing in Iran

“…The free-radical-scavenging activity of the extracts, SPE fractions and isolated glycosides (1-3) were determined by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free-radical-scavenging assay (Kumarasamy et al, 2002(Kumarasamy et al, , 2007 (Table 3). The MeOH extract showed the highest level of activity with a RC50 value of 1.15 ×10 -1 mg/mL among all extracts, and most of its activity was contributed by the SPE fractions of 40% and 60% aq.…”

“…The free-radical-scavenging effect of the extracts, fractions and isolated compounds was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay (Kumarasamy et al, 2002(Kumarasamy et al, , 2007. DPPH was obtained from Fluka Chemie AG, Bucks and a solution of DPPH (0.08 mg/mL) in methanol was used.…”

Bioactivity of two Turkish endemic Centaurea species, and their major constituents

“…Quercetin was obtained from Avocado Research Chemicals Ltd, Shore road, Heysham, Lancs. The method used by Takao et al (1994) was adopted with suitable modifi cations (Kumarasamy et al 2002). DPPH (4 mg) was dissolved in MeOH (50 mL) to obtain a concentration of 80 μg/mL.…”