Bioanalysis of (1R,4R,5S,6R)-4-Amino-2-Oxabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid (Ly379268) in Rat Plasma Using Derivatization Liquid Chromatography/Mass Spectrometry

Benitex, Yulia; Luan, F; Shields, Eric; McNaney, Colleen A.; Morgan, Daniel G.; Olah, Timothy; Drexler, Dieter M.

doi:10.4155/bio.14.103

Bioanalysis

2014

DOI: 10.4155/bio.14.103

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Bioanalysis of (1R,4R,5S,6R)-4-Amino-2-Oxabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid (Ly379268) in Rat Plasma Using Derivatization Liquid Chromatography/Mass Spectrometry

Yulia Benitex

F Luan

Eric Shields

et al.

Abstract: Chemical derivatization of a low-molecular-weight and highly polar molecule yields a derivative that is retained on a reversed-phase liquid chromatography column with improved tandem mass spectrometric response.

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Bioanalysis of (1R,4R,5S,6R)-4-Amino-2-Oxabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid (Ly379268) in Rat Plasma Using Derivatization Liquid Chromatography/Mass Spectrometry

Abstract: Chemical derivatization of a low-molecular-weight and highly polar molecule yields a derivative that is retained on a reversed-phase liquid chromatography column with improved tandem mass spectrometric response.

Cited by 0 publications

References 12 publications

No citations

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