Biochemical analysis of cultivated mushroom, Pleurotus florida and synthesis of silver nanoparticles for enhanced antimicrobial effects on clinically important human pathogens

Priyadarshni, K.C; Krishnamoorthi, Raman; Mumtha, Chelladurai; Mahalingam, Pambayan Ulagan

doi:10.1016/j.inoche.2022.109673

Cited by 20 publications

(13 citation statements)

References 54 publications

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“…Krishnamoorthi et al 2021 reported that Au NPs obtained from A. bisporus , which have great antifungal potential in C. albicans and A. fumigatus at 100 µg/ml [111] . The findings of Priyadarshni et al 2022, green synthesis of Ag NPs with mushroom extract have antifungal efficacy in A. fumigatus and C. albicans [164] . Various fungal pathogens are more susceptible for Ag/Au NPs and their particular antifungal mechanism are displayed in Table 5 .…”

Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 95%

“…Nanomaterials reveals antimicrobial property by promoting antibiotics administration effectiveness and safety [86] , [93] , [164] . The antimicrobial property of NPs cannot pose direct and severe consequence, while promising toxicity upon long-term exposure.…”

Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 99%

“…Priyadharshni et al, (2022) reported that, the synergistic antimicrobial effects of Ag NPs and mushroom extract showed efficient antibacterial effects against human pathogens and Ag NPs with mushroom extract may be attributed by their tiny size and large surface area to contact the microbial cells and thus makes them interact effectively with the cell wall of the disease causing microbes [164] . The mushroom based Au NPs may bind with the cytoplasmic membrane and destroys the bacterial cell due to the electrostatic affinity between positively charged Au NPs and negatively charged cell membrane of the pathogenic microbes [111] .…”

Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 99%

See 2 more Smart Citations

Nanomedicine for drug resistant pathogens and COVID-19 using mushroom nanocomposite inspired with bacteriocin – A review

Srinivash

Krishnamoorthi

Mahalingam

et al. 2023

Inorganic Chemistry Communications

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Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 95%

Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 99%

Section: Bio-functional Potential Of Metal Npsmentioning

confidence: 99%

See 1 more Smart Citation

Nanomedicine for drug resistant pathogens and COVID-19 using mushroom nanocomposite inspired with bacteriocin – A review

Srinivash

Krishnamoorthi

Mahalingam

et al. 2023

Inorganic Chemistry Communications

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“…The utilized mushroom spawns of Pleurotus floridanus (PF strain) were purchased from the Agricultural Research Center, Cairo, Egypt. The mushroom was cultivated as described in Supplementary Material and as reported in recent studies [37,38].…”

Section: Collection Of Mushroom Spawn and Other Chemicalsmentioning

confidence: 99%

Biosynthesis, Spectrophotometric Follow-Up, Characterization, and Variable Antimicrobial Activities of Ag Nanoparticles Prepared by Edible Macrofungi

et al. 2023

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The biosynthesis of silver nanoparticles (Ag NPs) could play a significant role in the development of commercial antimicrobials. Herein, the biosynthesis of Ag NPs was studied using the edible mushroom Pleurotus floridanus, and following its formation, spectrophotometry was used to detect the best mushroom content, pH, temperature, and silver concentration. After that, the morphology was described via transmission electron microscopy (TEM), and nanoscale-size particles were found ranging from 11 to 13 nm. The best conditions of Ag content and pH were found at 1.0 mM and 11.0, respectively. In addition, the best mushroom extract concentration was found at 30 g/L. According to XRD analysis, the crystal structure of the formed amorphous Ag NPs is cubic with a space group of fm-3m and a space group number of 225. After that, the function groups at the surface of the prepared Ag NPs were studied via FTIR analysis, which indicated the presence of C=O, C-H, and O-H groups. These groups could indicate the presence of mushroom traces in the Ag NPs, which was confirmed via the amorphous characteristics of Ag NPs from the XRD analysis. The prepared Ag NPs have a high impact against different microorganisms, which could be attributed to the ability of Ag NPs to penetrate the cell bacterial wall.

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“…Vitamins, such as riboflavin, thiamin, folic acid, ascorbic acid, and ergosterol, and minerals, such as phosphorus, selenium, magnesium, and copper, are widely distributed throughout the fruiting bodies of many mushrooms. Fruiting bodies are abundant in β-glucans, chitin, and dietary fibers [ 2 , 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Comprehensive Analysis of Bioactive Compounds in Wild Ganoderma applanatum Mushroom from Kerala, South India: Insights into Dietary Nutritional, Mineral, Antimicrobial, and Antioxidant Activities

Rijia,

Krishnamoorthi,

Rasmi

et al. 2024

Pharmaceuticals

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The present study focused on the mushroom Ganoderma, which has been used in Eastern countries for centuries as a food and medicinal source. Specifically, the fruiting bodies of Ganoderma applanatum from the Kerala Forest Research Institute in Thirussur, Kerala, India, were analyzed for their nutritional and medicinal properties. The methanolic extracts of G. applanatum were used to examine secondary metabolites and proximate profiles, revealing the presence of various phytochemicals such as terpenoids, phenolics, glycosides, alkaloids, flavonoids, and saponins. Further analysis revealed the presence of significant amounts of calcium, sodium, phosphorus, and manganese. The compounds were characterized using chromatographic analysis, FTIR, and GC-MS, which revealed potential therapeutic compounds with C-H and C-O bonds in the amide group, β-glycosides, and C-C/C-O vibrations of phenolic substances. Mushroom extract at a concentration of 100 µg mL−1 exhibited potent antimicrobial activity against various pathogens. This study suggests that G. applanatum has a rich biochemical composition and pharmacological potential, making it a promising candidate for drug development and traditional medicine, and contributes valuable insights into its diverse therapeutic applications.

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Biochemical analysis of cultivated mushroom, Pleurotus florida and synthesis of silver nanoparticles for enhanced antimicrobial effects on clinically important human pathogens

Cited by 20 publications

References 54 publications

Nanomedicine for drug resistant pathogens and COVID-19 using mushroom nanocomposite inspired with bacteriocin – A review

Nanomedicine for drug resistant pathogens and COVID-19 using mushroom nanocomposite inspired with bacteriocin – A review

Biosynthesis, Spectrophotometric Follow-Up, Characterization, and Variable Antimicrobial Activities of Ag Nanoparticles Prepared by Edible Macrofungi

Comprehensive Analysis of Bioactive Compounds in Wild Ganoderma applanatum Mushroom from Kerala, South India: Insights into Dietary Nutritional, Mineral, Antimicrobial, and Antioxidant Activities

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