2023
DOI: 10.1111/trf.17519
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Biochemical and functional characteristics of stored (double‐dose) buffy‐coat platelet concentrates treated with amotosalen and a prototype UVA light‐emitting diode illuminator

Nathalie Brouard,
Floriane Pissenem‐Rudwill,
Clarisse Mouriaux
et al.

Abstract: BackgroundPathogen reduction of platelet concentrates (PCs) using amotosalen and broad‐spectrum UVA illumination contributes to the safety of platelet transfusion by reducing the risk of transfusion‐transmitted infections. We evaluated the in vitro quality of stored buffy‐coat (BC) PCs treated with amotosalen and a prototype light‐emitting diode (LED) illuminator.MethodsDouble‐dose BC‐PCs collected into PAS‐III/plasma or SSP+/plasma (55/45%) were treated with amotosalen in combination with either conventional … Show more

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