Biochemical, Clinical and Prevalence Characteristics of Chronic Kidney Disease Secondary to Arterial Hypertension

Abstract

Hypertension has been recognized as an important cause of chronic kidney disease (CKD). As the most important part of the hypertensive patients are managed in primary care, implementation of routine early detection of CKD by determination of albuminuria and the estimated glomerular filtration rate (eGFR) at this level is essential for diagnosis and prevention. The present study demonstrated that prevalence of chronic kidney disease in hypertensive patients was 13.32%, being higher in female than men, with old age and in the presence of diabetes mellitus and associated cardiovascular diseases. The reduction of the eGFR depended significant statistically on age, gender and presence of diabetes mellitus, while albuminuria depended on the presence of diabetes and old age. Early detection of CKD in hypertensive patients permits optimal treatment of cardiovascular risk factors, especially concerning the reduction of high blood pressure, therapy with renin-angiotensin system blockers in order to reduce albuminuria and the progression of eGFR decline and treatment of hyperlipidaemia.