Diabetes, especially type 2 diabetes mellitus (T2DM), the prevalence continues to increase, with the largest increase occurring in low and middle income countries. The active content of aloe vera functions as antioxidants, flavonoids, regulates body weight and antihyperglycemic, namely acemannan and glucomannan, which are included in the Liliaceae family and are succulent plants, shrubs, xerophytes commonly used to treat wound healing, microbial infections, skin diseases and inflammation. This study aims to analyze the effect of aloe vera juice before meals on fasting blood sugar levels in T2DM patients with an analytical study. Pre-post Test Control Group Design was used in the research design. The subjects were given aloe vera juice before lunch in the treatment group while the control group was given mineral water. Based on the results of statistical tests, there was a significance (p value = 0.022) in the aloe vera juice group and in the control group p value = 0.094. There is an effect of giving aloe vera juice to T2DM patients who are given lunch while there is no effect in the control group who is given mineral water. Further research on the effect of pre-meal aloe vera juice on cholesterol is recommended.