Biochemical Constituents of the Dura Mater in Vitamin a Deficiency

Cousins, R. J.; Eaton, H.D.; Rousseau, Jean-Jacques; Hall, R.C.

doi:10.1093/jn/97.3.409

Cited by 27 publications

(7 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hypo- and hypervitaminosis A does result in significant morphological changes in the AV. It has been reported that changes in the dura involve the mucopolysaccharides moiety and that since the AV are rich in mucopolysaccharides it could directly affect the integrity of these structures and decreased functional abilities [ 34 , 87 , 88 ]. Thinning of the AV cell cap and interstitial fibrosis have also been reported and associated with increased resistance to CSF outflow and absorption [ 88 , 89 ].…”

Section: Reviewmentioning

confidence: 99%

“…It has been reported that changes in the dura involve the mucopolysaccharides moiety and that since the AV are rich in mucopolysaccharides it could directly affect the integrity of these structures and decreased functional abilities [ 34 , 87 , 88 ]. Thinning of the AV cell cap and interstitial fibrosis have also been reported and associated with increased resistance to CSF outflow and absorption [ 88 , 89 ]. The fact that the observed increase in CSF pressure does not result in the development of hydrocephalus suggests that the lymphatic system may remain intact and provide an effective alternate pathway for CSF drainage.…”

Section: Reviewmentioning

confidence: 99%

See 1 more Smart Citation

The function and structure of the cerebrospinal fluid outflow system

Pollay¹

2010

Fluids Barriers CNS

304

223

View full text Add to dashboard Cite

This review traces the development of our understanding of the anatomy and physiological properties of the two systems responsible for the drainage of cerebrospinal fluid (CSF) into the systemic circulation. The roles of the cranial and spinal arachnoid villi (AV) and the lymphatic outflow systems are evaluated as to the dominance of one over the other in various species and degree of animal maturation. The functional capabilities of the total CSF drainage system are presented, with evidence that the duality of the system is supported by the changes in fluid outflow dynamics in human and sub-human primates in hydrocephalus. The review also reconciles the relative importance and alterations of each of the outflow systems in a variety of clinical pathological conditions.

show abstract

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

The function and structure of the cerebrospinal fluid outflow system

Pollay¹

2010

Fluids Barriers CNS

304

223

View full text Add to dashboard Cite

show abstract

“…This is the earliest deficiency sign observed, and coincides with the first decline in weight gain (Cousins et a/., 1969). This is the earliest deficiency sign observed, and coincides with the first decline in weight gain (Cousins et a/., 1969).…”

Section: Growthmentioning

confidence: 51%

Vitamins E and A

Budowski¹,

Sklan²

1989

Role of Fats in Human Nutrition

View full text Add to dashboard Cite

“…The etiology of the increased intracranial pressure is due to a pseudotumor effect rather than to hydrocephalus. Animal models of hypovitaminosis A suggest that the increased pressure is a consequence of increased resistance to cerebrospinal fluid absorption at the arachnoid villi (11, [13][14][15].…”

Section: Discussionmentioning

confidence: 99%

Vitamin A in Cystic Fibrosis

Eid,

Shoemaker,

Samiec

1990

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

Much has been learned about vitamin A physiology in the last 50 years, yet few changes have been made in therapy. Unfamiliarity with vitamin A bioavailability and distribution may inadvertently result in toxicity. A literature search demonstrates that hypovitaminosis A has rarely been reported in patients with cystic fibrosis, and may manifest very differently in children of different ages. Furthermore, hypervitaminosis A may present with similar features, and can result from correction of deficiency. We report such a case in a 4.5‐month‐old infant, newly diagnosed with cystic fibrosis, who suffered first from vitamin A deficiency and then vitamin A toxicity. A brief review of vitamin A physiology, deficiency, and toxicity is presented.

show abstract

Biochemical Constituents of the Dura Mater in Vitamin a Deficiency

Cited by 27 publications

References 23 publications

The function and structure of the cerebrospinal fluid outflow system

The function and structure of the cerebrospinal fluid outflow system

Vitamins E and A

Vitamin A in Cystic Fibrosis

Contact Info

Product

Resources

About