“…Low affinity of tubulin for MBC is probably a common mechanism of resistance binding constant of 2.5 x 10 a liters/mol. In the last 15 years several benzimidazole compounds have been introduced as fungicides, like benomyP (29), fuberidazole (58), and thiabenda-1The following common names and abbreviations are used: benomyl, methyl 1-(butylcarbamoyl)benzimidazol-2-yl carbamate; fuberidazole, 2-(2'-furyl)benzimidazole; thiabendazole, 2-(4'-thiazolyl) benzimidazole; fenbenda-zole (66), as anthelmintics, like fenbendazole (5), mebendazole (68), parbendazole (1), and thiabenzole, methyl 5-phenylthiobenzimidazol-2-yl carbamate; mebendazole, methyl 5-benzoylbenzimidazoi-2-yl carbamate; parbendazole, methyl 5-butylbenzimidazol-2-yl carbamate; oncodazole or R 17934, methyl 5-(2-thienylcarbonyl)benzimidazol-2-yl carbamate; carbendazim or MBC, methyl benzimidazol-2-yl carbamate; SDS, so- dazole (12), or as antitumoral drug, like oncodazole or R 17934 (3,4). Structural formulas of these compounds are shown in Fig.…”