Biochemical Features in Rats with Different Behavioral Activity under Conditions of Emotional Stress

Abstract

Adaptive capacities of the organism under conditions of emotional stress are determined by individual complex of anti-stress protective mechanisms. We studied the content of coenzyme Q10 and the spectrum of polyunsaturated fatty acids omega-3 and omega-6 in the serum, liver, and brain, and LPO intensity in the serum and liver of behaviorally active and passive rats under conditions of acute emotional stress. The differences in the formation of adaptive responses in animals with various behavioral activities were demonstrated.

The effect of separate and combined action of lead oxide and gamma radiation on immunological reactivity and biochemical processes in the organs of immunogenesis

“…Thus, after gamma radiation at a dose of 0.2 Gy and the action of lead oxide, the concentration of CIC in the blood serum increases, the relative and absolute number of CD19+ lymphocytes subpopulation decreases. According to the results obtained, it can be judged that the combined effect of radiation and lead oxide causes the activation of LP in the spleen, with a decrease in nonspecific phagocytic resistance of the body causes depression of the humoral link of immunity [26,35].…”

“…An integral part of oxidative metabolism is LP, which is one of the pathogenesis factors of a number of diseases and is part of the adaptive mechanism of the body [23,26,29]. As a result of the activation of LP and the accumulation of free radicals, the structural and functional integrity of cell membranes is disrupted, lysosomal enzymes are released, which eventually leads to pathological processes in the cell and in the body as a whole [24].…”