Biochemical, genotoxic, histological and ultrastructural effects on liver and gills of fresh water fish Channa punctatus exposed to textile industry intermediate 2 ABS

Sharma, Kusha; Sharma, Prince; Dhiman, Shakti Kumar; Chadha, Pooja; Saini, Harvinder Singh

doi:10.1016/j.chemosphere.2021.132103

Cited by 43 publications

(8 citation statements)

References 79 publications

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“…Invasion by ROS initiates antioxidant defense activities in the intestines, muscles, and gills of zebrafish. However, the defense system is insufficient for complete removal, leading to lipid peroxidation (Sharma et al 2022). This was confirmed by the significant increase in MDA levels in the 10 mg/L experimental group.…”

Section: Discussionmentioning

confidence: 70%

“…This suggests a synergistic effect of SOD and CAT on ROS scavenging (Si et al 2019). Increased CAT activity indicates activation of the cellular antioxidant defense system to repair oxidative stress damage by scavenging and breaking down excess H 2 O 2 (Sharma et al 2022). Specifically, intestinal CAT activity decreased significantly after 20-25 d. This may be because of the large amount of CAT used to eradicate H 2 O 2 after a sustained H 2 O 2 surge after continuous zinc exposure.…”

Section: Discussionmentioning

confidence: 99%

“…The present study showed that short-term (5 d) zinc exposure significantly increased SOD activity in the intestine, which is a marker for the activation of the antioxidant system. Zebrafish are stressed by zinc, and excessive ROS production in cells stimulates SOD activity to effectively regulate the balance of ROS (Sharma et al 2022). In the mid-exposure period (10-15 d), under the action of SOD, the level of ROS gradually returned to a steady state, and SOD returned to its original state.…”

Section: Discussionmentioning

confidence: 99%

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Oxidative stress, neurotoxicity, and intestinal microbial regulation after a chronic zinc exposure: an experimental study on adult zebrafish (Danio rerio)

Yuan

et al. 2023

Journal of Water Reuse and Desalination

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Zinc is one of the heavy metals present in textile wastewater with high concentrations. However, the chronic toxic effects of zinc on aquatic vertebrates are still ambiguous. Zinc accumulation in zebrafish after chronic zinc exposure and toxic effects on the intestines, muscles, and gills were investigated in this study. The results showed that a significant accumulation of zinc in the intestine, muscle, and gill was observed after 25 d of zinc exposure. The toxic effects of zinc were mainly in the form of zinc-induced oxidative stress in zebrafish, potential neurotoxicity, and changes in intestinal microbes. Significant changes in the levels of superoxide dismutase, catalase, metallothionein, glutathione, and malondialdehyde indicated that zinc damaged the antioxidant system of adult zebrafish. Zinc exposure resulted in a significant decrease in acetylcholinesterase activity and abnormal neural signaling. Furthermore, zinc exposure resulted in increased intestinal microbial richness and decreased the Simpson index in adult zebrafish. At the phylum and genus levels, the predominant microbes in the intestine are altered by zinc. In summary, this study provides an analysis of the toxic effects of chronic zinc exposure on adult zebrafish and the potential mechanisms, which are important for assessing the dual effects of zinc on aquatic organisms.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Oxidative stress, neurotoxicity, and intestinal microbial regulation after a chronic zinc exposure: an experimental study on adult zebrafish (Danio rerio)

Yuan

et al. 2023

Journal of Water Reuse and Desalination

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“…The microstructure of suanyu blocks was analysed using scanning electron microscopy (SEM), determined by the method described by Sharma et al . (2022) with minor modifications. The dorsal muscles of the samples were cut into blocks of approximately 6 mm × 6 mm × 3 mm and fixed in 2.5% glutaraldehyde solution.…”

Section: Methodsmentioning

confidence: 99%

Dynamic changes and correlation analysis of protease activities, texture and flavour compounds during fish fermentation (suanyu) using mixed culture (Enterococcus rivorum and Enterococcus lactis)

Zhang

Feng

et al. 2023

Int J of Food Sci Tech

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This research investigated the dynamic changes and correlations of protease activity, material texture and flavour compounds during the fermentation (13 days) of crucian (Carassius auratus). Mixed starter fermentation (Enterococcus rivorum and Enterococcus lactis) and natural fermentation were used for the study. Results showed that the protease activity, TCA-soluble protein and flavour substances were increased with fermentation time and were higher in the mixed fermentation group. The results of relative odour activity value showed that some aldehydes played a major role in the flavour of the product, such as octanal, nonanal and (E)-2-nonenal. The correlation analysis showed that protease activity and material texture (hardness and chewiness) had a significantly positive correlation with many flavour compounds (octanal, nonanal, glutamic acid, etc.). This work will provide a theoretical reference for the application of mixed starter cultures and for improving the quality of suanyu by increasing protease activity and changing the texture of the material.

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“…The characterization of exposure effects to contaminants is one of the stages of the environmental risk assessment (ERA) framework, which establishes essential guidelines to drive the decision making on relevant environmental issues and aims to improve the quality of life through management, preservation and conservation of the environment (EPA 1998). Upon stressors' exposure, organisms may undergo differential biological responses at morpho-physiological functions that can occur in a broader range of biological levels (from cells, tissues, organs to ecosystem level) (Sharma et al 2022). Therefore, to achieve a complete and integrative overview of an organism's health, a multi-level biomarker approach, including biochemical, behavioral, genotoxic, physiological, molecular and histopathological markers, has been widely used within ERA (Samanta et al 2018;Lomartire et al 2021).…”

Section: Introductionmentioning

confidence: 99%

Improvements in histological technique for the ecotoxicological assessment using small biological samples

Santana

Damasceno

Loureiro

et al. 2022

Preprint

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Histological techniques consist of traditional and very important tools for a better understanding of cellular morphology and physiology in ecotoxicological studies. Despite bioassays generally recommending the use of small test organisms, based on some advantages as their low maintenance costs and large replicates’ number, the histological processing of small organisms is not commonly used due to demanding laboratorial handling. The present study proposes an accessible protocol for a histological method in fish larvae with a maximum length of 8 mm, as well as the use of histopathological biomarkers on Senegal sole larvae for ecotoxicological testing. Eight-day old larvae of Solea senegalensis obtained from breeders' natural spawns in cultivation conditions were submitted to histological processing by an adjusted protocol comprising fixation, agarose array pre-embedding, paraffin embedding, slides preparation, and image analysis by light optical microscope coupled to a digital camera. Low-cost and easy-to-use alternatives were applied in the technique execution. The histological steps were detailed and the multiple tissues and cellular structures of the S. senegalensis larvae were described and discussed. This can be considered a valuable background information for ecotoxicological studies where changes in cell morphology and physiology are expected.

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Biochemical, genotoxic, histological and ultrastructural effects on liver and gills of fresh water fish Channa punctatus exposed to textile industry intermediate 2 ABS

Cited by 43 publications

References 79 publications

Oxidative stress, neurotoxicity, and intestinal microbial regulation after a chronic zinc exposure: an experimental study on adult zebrafish (Danio rerio)

Oxidative stress, neurotoxicity, and intestinal microbial regulation after a chronic zinc exposure: an experimental study on adult zebrafish (Danio rerio)

Dynamic changes and correlation analysis of protease activities, texture and flavour compounds during fish fermentation (suanyu) using mixed culture (Enterococcus rivorum and Enterococcus lactis)

Improvements in histological technique for the ecotoxicological assessment using small biological samples

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