Biochemical Markers of Oxidative Stress in Tissues of Broiler Chickens Fed Zinc Bacitracin and Ascorbic Acid under Hot Climate

Ismail, I.B.; Busadah, Khalid Ahmed Al; Bahr, S.M. El

doi:10.3923/ijbc.2015.38.45

Cited by 9 publications

(10 citation statements)

References 15 publications

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“…Additionally, broilers fed zinc bacitracin in the diet showed a decrease in enzymatic antioxidants (superoxide dismutase and catalase) (El-Bahr et al 2013). Previous results demonstrated also that, zinc bacitracin in the diet decreased levels of serum enzymatic antioxidants besides increased the lipid peroxidation level (Malondialdehyde) (Ismail et al 2015). Moreover, zinc bacitracin and bacitracin methylene disalicylate induced a nonsignificant reduction in superoxide dismutase and catalase but malonaldehyde increased (Zhou et al 2016) and (Chowdhury et al 2018), respectively.…”

Section: Discussionmentioning

confidence: 86%

Comparative studies on the effects of lincomycin and bacitracin on hematobiochemical and immunological parameters in broiler chickens

Elkomy

Farag

Elgharbawy

et al. 2019

IJPT

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A total of 100 one-day-old healthy broiler chicks were used to study the effects of lincomycin and bacitracin on some hematobiochemical and immunological parameters. Chicks were divided into four equal groups, 25 each. The first group was kept as control; the 2nd group was received 0.5 g of lincomycin per liter; the 3rd group was received 100 mg bacitracin per liter and the 4th group was administered both lincomycin and bacitracin, each at the above-mentioned dose. Drugs were given in drinking water for 5 successive days from 20th to 25th day of age. Bodyweight was recorded at the beginning of the experiment and at 1st-day post administration where body performance was recorded. One day post administration, blood samples were collected for estimation of hematobiochemical and immunological alterations. The obtained results revealed that broiler chicks administered lincomycin or bacitracin or both revealed a marked increase in bodyweight, weight gain, phagocytic activity, phagocytic index, erythrocytic count, hemoglobin level, packed cell volume, total leukocytic count, serum total protein, albumin, total globulin, α, β and γ globulin. Furthermore, a significant elevation in malondialdehyde associated with a marked reduction in albumin-globulin ratio, serum total lipid, cholesterol and triglyceride and a significant decrease in catalase and superoxide dismutase, were recorded, compared with the control group. In conclusion, lincomycin and bacitracin either alone or in combination have positive impacts on growth performance, immunological and hematobiochemical parameters of broiler chickens. So, it is recommended to use both drugs as growth promoters in broiler chickens.

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Section: Discussionmentioning

confidence: 86%

Comparative studies on the effects of lincomycin and bacitracin on hematobiochemical and immunological parameters in broiler chickens

Elkomy

Farag

Elgharbawy

et al. 2019

IJPT

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“…Lipid peroxidation is a common manifestation of oxidative damage. The level of lipid peroxidation was assessed by measuring malondialdehyde (Ismail et al 2015), a sensitive and reliable indicator of oxidative stress in cells and tissues (Ayala et al 2014). The increased MDA levels observed in birds exposed to AFB1 indicates enhanced lipid peroxidation leading to tissue injury.…”

Section: Resultsmentioning

confidence: 99%

Effect of dietary supplementation of Eclitpa alba on oxidative stress and liver damage induced by aflatoxin in broilers

UMAYA

MANPAL

Krishnamoorthy

et al. 2018

Indian J of Anim Sci

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The primary aim of the present study was to evaluate the efficacy of Eclipta alba leaf powder to ameliorate the oxidative stress and liver damage induced by aflatoxin B1 (AFB1) in broilers. Day-old male broilers were fed with basal diet (control), basal diet supplemented with E. alba (1.0%), basal diet with 1.0 ppm AFB1 or AFB1 (1.0 ppm) with E. alba (1.0%) for 42 days. Birds fed AFB1 showed significantly higher serum AST and ALT activities, and decreased concentrations of total protein, cholesterol and albumin. AFB1 feeding significantly increased hepatic lipid peroxidation products, decreased antioxidant enzymes and induced pathological changes in liver. The supplementation of E. alba leaf powder with AFB1 contaminated diet significantly improved serum biochemical profile, reduced the oxidative stress and pathological changes in liver. The present study revealed that supplementation of E. alba reduces the liver damage and oxidative stress induced by AFB1 and offer protection against aflatoxin toxicity in broilers.

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“…Ascorbic acid (AA) is an antioxidant which scavenges stress-induced free radicals in poultry birds (Ismail et al, 2015). Betaine (BET) exerts methyl-donor, osmolyte (Amerah & Ravindran, 2015) and antioxidant properties in poultry birds (Alirezaei et al, 2012).…”

Section: Objectivementioning

confidence: 99%

Dietary ascorbic acid and betaine improve stress responses, testosterone levels and some sexual traits in male Japanese quails during the dry season

et al. 2021

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The experiment investigated the effects of dietary ascorbic acid and betaine stress responses, serum testosterone levels, and some sexual traits in male Japanese quails during the dry season. A total of 240 male Japanese quails (14 days old) were used and randomly assigned to four groups, each group has three replicates (n = 20). Birds in treatment groups were fed ascorbic acid (AA); betaine (BET); and AA + BET in their diets, whereas the control birds were fed only basal diet. Environmental conditions were predominantly outside thermoneutral zone for Japanese quails. Dietary AA ± BET increased (p < .05) serum catalase, reduced glutathione and testosterone, but lowered (p < .05) cortisol levels when compared with control group. Supplemental AA, BET, or AA + BET enhanced (p < .05) cloacal gland size and sexual traits. In conclusion, dietary AA and BET improved stress responses, serum testosterone levels, and some sexual traits in male Japanese quails during the dry season.

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Biochemical Markers of Oxidative Stress in Tissues of Broiler Chickens Fed Zinc Bacitracin and Ascorbic Acid under Hot Climate

Cited by 9 publications

References 15 publications

Comparative studies on the effects of lincomycin and bacitracin on hematobiochemical and immunological parameters in broiler chickens

Comparative studies on the effects of lincomycin and bacitracin on hematobiochemical and immunological parameters in broiler chickens

Effect of dietary supplementation of Eclitpa alba on oxidative stress and liver damage induced by aflatoxin in broilers

Dietary ascorbic acid and betaine improve stress responses, testosterone levels and some sexual traits in male Japanese quails during the dry season

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