Biochemical, Phytochemical Screening and Pharmacological Potential of Allamanda blanchetii (Purple Allamanda)

Abstract

One of the significant members of the perennial, terrestrial plant family Apocynaceae is Allamanda blanchetii. Its gorgeous blossom has led to its cultivation as an ornamental plant. Many ailments can be cured using medicinal herbs. We have presented the preliminary analysis of A. blanchetii in this work. In this work, we have provided a phytochemical analysis of A. blanchetii, which may suggest that it has therapeutic potential. The chloroform, acetone, and methanol leaf extract has been demonstrated to contain flavonoids, saponins, terpenoids, and tannins. We also research A. blanchetii biological makeup. Three different chlorophyll concentrations are shown: total chlorophyll (4.90 mg/g tissue), chlorophyll a (2.78 mg/g tissue), and chlorophyll b (2.71 mg/g tissue). carbs (35.30%), protein (23.5%), and fat (3.5%). While using thin layer chromatography (TLC) to detect different chemical compositions, the results revealed that the Rf value was 0.56 and that the colour band was yellowish. by adopting the AOAC standard technique, it is possible to study the pharmacological potential using variables such as moisture content, ash value, and extractive value in alcohol and water. The results show that there is 78.96% moisture content, 21.03% ash value, 30.40% extractive value in water, and 40.30% alcohol. The study’s findings indicate that A. blanchetii has therapeutic qualities and is useful for human society.

Computational investigation of phytochemicals from Allamanda cathartica as a potent agonist of Peroxisome proliferator-activated receptor-gamma (PPARγ) for the treatment of Diabetes mellitus

“…The entire plant is used to treat skin burns. It is effective against jaundice, malaria, and fungal infections, as well as having antithrombotic, immunomodulatory, cardiovascular, anti-ischemic, antiarrhythmic, antiangiogenic, antimutagenic, and gastroprotective properties (Prabhadevi et al, 2012;Rodrigues et al, 2020;Dokhe et al, 2023). Long-chain esters, triterpene esters, isoplumericin, plumericin, and plumeride are found in the roots.…”