Biochemical properties, antibacterial and cellular antioxidant activities of buckwheat honey in comparison to manuka honey

Deng, Jianling; Liu, Rui; Lu, Qun; Hao, Peiyan; Xu, Anqi; Zhang, Jiu‐liang; Tan, Jun

doi:10.1016/j.foodchem.2018.01.115

Cited by 140 publications

(93 citation statements)

References 37 publications

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“…Manuka honey contains relatively high levels of methylglyoxal (MGO), which has been identified to be unique to this type of honey and directly contributes to Manuka honey's antibacterial abilities. 43,44 This compound also occurs in humans as a by-product to metabolic processes, such as glycolysis 45 ; however, it has been shown to exhibit potentially toxic side effects, including the ability to modify DNA and other macromolecules. 46 Additionally, in healthy human cells, the tripeptide glutathione (GSH) is capable of suppressing the activity of MGO 47 ; however, once a cell becomes damaged, such as during the oral conditions discussed in this review, there is a reduction in the expression of GSH.…”

Section: Future Research Proposalsmentioning

confidence: 99%

“…2). While Manuka honeys have demonstrated substantial potential wound healing abilities in vitro and in vivo, 11,44,50 there is currently a lack of relevant clinical trials utilizing this product for wound healing treatments. Due to its compositional properties, it should be considered that Manuka honey be utilized in clinical trials for site-specific topical application in wound sites other than the oral cavity, such as a laceration or burn on the skin to test for effectiveness and tolerability.…”

Section: Future Research Proposalsmentioning

confidence: 99%

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The Effect of Honey as a Treatment for Oral Ulcerative Lesions: A Systematic Review

Hunter

Kellett

D’Cunha

et al. 2020

Exploratory Research and Hypothesis in Medicine

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Background and objectives: A healthy oral environment features a rapid turnover rate of epithelium cells capable of regeneration and repair, with the oral epithelium contributing as a physical barrier and immune defense. However, the oral cavity can be subjected to unique damage, such as ulcerations. Honey is reported as a therapeutic agent for wound healing, due to its antioxidant, antibacterial and anti-inflammatory properties. Methods: A systematic review was performed following the PRISMA 2015 Guidelines, to assess the efficacy and safety of the therapeutic use of honey in the oral cavity. Four electronic databases were searched (PubMed, Cochrane Library, Scopus, and Web of Science) for randomized controlled trials examining the effect of honey on oral cavity conditions. Results: In total, 2,832 records were identified, and after applying exclusion criteria, 13 studies were included. Honey was applied topically throughout, for chemotherapy or radiotherapy-induced oral mucositis (n = 11), dental wounds (n = 1), and recurrent aphthous stomatitis (n = 1), all of which are ulcerations with different pathologies. In the majority of studies (12/13), honey reduced the severity and/or duration of the condition compared with control groups (all p<0.05). However, a group treated with Manuka honey (n = 1) experienced adverse effects and considerable participant attrition. Conclusions: Honey is an effective treatment for a range of oral ulcerative conditions. Future research should focus on compositional analysis of honeys to determine those with optimal beneficial properties, and whether Manuka honey is safe to use in the oral cavity.

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Section: Future Research Proposalsmentioning

confidence: 99%

Section: Future Research Proposalsmentioning

confidence: 99%

The Effect of Honey as a Treatment for Oral Ulcerative Lesions: A Systematic Review

Hunter

Kellett

D’Cunha

et al. 2020

Exploratory Research and Hypothesis in Medicine

View full text Add to dashboard Cite

show abstract

“…The composition of this natural food includes sugars, mostly glucose and fructose, the ratio of which determines the degree of granulation for a honey [16]. Disaccharide and maltose sugars are also present [17]. Components found in lesser quantities include organic acids, amino acids, proteins, enzymes, minerals, lipids, vitamins [18,19], and hydroxymethylfurfural, which is used as an indicator of freshness [20,21].…”

Section: Honey and Other Apiculture Productsmentioning

confidence: 99%

American Foulbrood and the Risk in the Use of Antibiotics as a Treatment

Mejías¹

2020

Modern Beekeeping - Bases for Sustainable Production

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Honeybees (Apis mellifera) crucially pollinate agricultural crops and endemic species, in addition to producing various apiculture products. The most economically relevant and abundant beehive product is honey, a sweet substance made from the secretions of melliferous plants. Honey is a natural food rich in nutrients, including certain bioactive compounds inherited from floral nectar and pollen. Among the most dangerous diseases for bees is American foulbrood. Spores of the causative microorganism, Paenibacillus larvae, can contaminate larvae food or the operculum wax in which larval stages of honeybees are kept. Infection is further promoted by common apiculture practices, such as reusing inert material contaminated with spores, even after months of storage. American foulbrood is untreatable, and management implicates completely incinerating the infected hive and all material that could have come into contact with pathogenic spores. The purpose of such drastic measures is to decrease propagation risk for other beehives. While evidence indicates that antibiotics could effectively control and combat this disease; antibiotic use is prohibited in most honey-producing countries due to increased risks to microbial resistance. Antibiotic residues in honey can affect consumer health, since the natural biological attributes of honey can be altered.

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“…aureus, E. coli, P. aeruginosa, Proteus mirabilis, coagulase-negative Staphylococcus, Streptococcus pyogenes and K. pneumonia. Most studies focused on a wide range of geographical and botanical origins have been reported in Saudi Arabia (Ghramh et al, 2018), India (Kateel et al, 2018), China (Deng et al, 2018), Brazil (Bueno-Costa et al, 2016), Pakistan (Khalil et al, 2014), Australia (Wong et al, 2017), Spain (Osés et al, 2016), Malaysian (Tan et al, 2009), New Zealand (Lin et al, 2011), Mexican honey (Rodríguez et al, 2012). These studies provide an essential international perspective because the antimicrobial activity of honey obviously differs based on the composition, which is mainly dependent on geographical and botanical origins and postharvest treatment (Deng et al, 2018;Kiriakou et al, 2018).…”

Section: Antibacterial and Antifungal Activitiesmentioning

confidence: 99%

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

Tahir

Mariod

Mahunu

et al. 2019

Journal of Apicultural Science

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Honey production in Africa is considered an integral part of folk medicine and provides an opportunity for poor rural communities to increase their economic sustainability. In this review, we provide and discuss the data available on the positive nutritional value and health properties of honey harvested from Africa. Besides sugar, honey contains protein and amino acids, with proline which is about 50% of the total amino acids, vitamins, enzymes, some minerals (Na, K, Mg, Ca, Zn, Cu, Mn, Fe, P, S), trace elements (Mn, Ni, Li, F, I, Cl, Sr, Co) and polyphenol compounds. The paper reviewed studies on the use of African honey with anti-inflammatory, antioxidant, antibacterial, antifungal, anti-breast cancer, antidiabetic and antimycotic properties and also its positive effects on infertility (asthenozoospermia), febrile neutropenia and diabetic foot ulcers.

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Biochemical properties, antibacterial and cellular antioxidant activities of buckwheat honey in comparison to manuka honey

Cited by 140 publications

References 37 publications

The Effect of Honey as a Treatment for Oral Ulcerative Lesions: A Systematic Review

The Effect of Honey as a Treatment for Oral Ulcerative Lesions: A Systematic Review

American Foulbrood and the Risk in the Use of Antibiotics as a Treatment

Chemical Composition, Nutritional Functions, and Antioxidant Activities of Honeys in Africa

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