2009
DOI: 10.1016/j.jembe.2009.02.004
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Biochemical response in gilthead seabream (Sparus aurata) to in vivo exposure to pyrene and fluorene

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Cited by 33 publications
(15 citation statements)
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“…In the present study, liver EROD activity was increased by the isolated Fl and Fluo exposures at the higher dosages, which was in agreement with a previous fi nding in C. auratus [4]. Conversely, linking the inability to bind to Ah-receptor (AhR) and initiate transcription [15,20], unapparent change or even inhibition of EROD activity by Fl and Fluo exposures has been reported in in vivo studies with other fi sh species, including zebrafi sh (Danio rerio) [21], gilthead seabream (Sparus aurata) [22], and mummichog (Fundulus heteroclitus) [15]. These results suggest that, unlike most HMW PAHs, the biochemical response to LMW PAHs may not be uniform among different fi sh species.…”
Section: Discussion Of Resultssupporting
confidence: 90%
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“…In the present study, liver EROD activity was increased by the isolated Fl and Fluo exposures at the higher dosages, which was in agreement with a previous fi nding in C. auratus [4]. Conversely, linking the inability to bind to Ah-receptor (AhR) and initiate transcription [15,20], unapparent change or even inhibition of EROD activity by Fl and Fluo exposures has been reported in in vivo studies with other fi sh species, including zebrafi sh (Danio rerio) [21], gilthead seabream (Sparus aurata) [22], and mummichog (Fundulus heteroclitus) [15]. These results suggest that, unlike most HMW PAHs, the biochemical response to LMW PAHs may not be uniform among different fi sh species.…”
Section: Discussion Of Resultssupporting
confidence: 90%
“…These results suggest that, unlike most HMW PAHs, the biochemical response to LMW PAHs may not be uniform among different fi sh species. Due to the great diversity found in some 28,000 fi sh species [23], there could be large intrinsic variations in the affi nity of the AhR of different fi sh species to small molecular-size PAH compounds [22,24]. Unlike Fl and Fluo, single exposure to Cu 2+ inhibited the liver EROD activity in C. auratus in this study, as also found in other fi sh species exposed to Cu 2+ [25][26][27].…”
Section: Discussion Of Resultssupporting
confidence: 69%
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“…Other information as in Fig. 1. in HSI are normally associated with enhanced detoxification activities in response to the presence of toxic compounds [38][39][40]. In this study, significant lower CF and HSI were observed in the VRP treated group with the highest concentration (E3 group), indicating a decrease in fish growth and overall condition caused by direct metabolic effect on fish.…”
Section: Morphological Indicesmentioning
confidence: 46%
“…Increases in HSI are normally associated with enhanced detoxifi cation activities in response to the presence of toxic compounds (Truscott et al, 1992;Pereira et al, 1993;Kopecka-Pilarczyk and Correia, 2009). In the present study, HSI in CBZ treatment groups with higher concentration (E2 and E3 groups) was lower than in the control, but was not statistically signifi cant (Fig.…”
Section: Gross Morphometric Indicesmentioning
confidence: 99%