Biochemical screening of Hisex brown cross chickens after multiple vaccinations

Abstract

It is impossible to imagine the epizootic well-being of poultry without immunoprophylaxis. Today, there are many vaccines to prevent infectious diseases in poultry. Our work aimed to determine how repeated vaccination affects the biochemical parameters of poultry serum. The post-vaccination changes in the protein, lipid, and enzyme metabolism of the poultry of the experimental group, which received repeated vaccine prophylaxis, are highlighted in the work. The obtained blood serum samples on the 1st, 15th, 25th, 50th, 75th, 100th, and 120th days of the chickens' life were analyzed using a semi-automatic biochemical analyzer for the content of glucose, total protein, albumins, globulins, bilirubin, creatinine, uric acid, and alpha-amylase activity, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, alkaline phosphatase, gamma glutamine transferase, and creatinine kinase. The conducted studies established an increase in indicators in the research group of 100-day-old chickens after the last vaccine prophylaxis complex compared to the control group, namely: hyperpotenemia by 8.6 %, hyperbilirubinemia by 19.6 %, hyperglycemia by 20.3 %, hyperenzymemia of alanine aminotransferase by 31 %, gamma glutamine transferase by 21.2 %, aspartate aminotransferase by 7.9 %, alpha-amylase by 3.9 %, alkaline phosphatase by 11.9 %, lactate dehydrogenase by 18.2 %. In connection with this, we can assume the stimulation of biochemical processes in the poultry's body against the background of vaccine prophylaxis.