Biochemistry of the adrenocortical hormones

Dorfman, Ralph I.

doi:10.1007/978-3-642-88385-9_3

Cited by 5 publications

(2 citation statements)

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“…A method is available for the detection and cellular localization of an enzyme, A5-3/Miydroxysteroid dehydrogenase (Wattenberg, 1958;Levy, Deane & Rubin, 1959), known to hold a key position in the synthesis of the various steroid hormones (Samuels, 1960;Dorfman, 1962;Deane & Rubin, 1965). We thought it would be valuable to study the activity of this enzyme in the steroid-hormone producing organs of the ferret.…”

Section: Introductionmentioning

confidence: 99%

5-3 -Hydroxysteroid Dehydrogenase Activity in the Steroid-Hormone Producing Organs of the Ferret (Mustela Putorius Furo)

Galil¹,

Deane²

1966

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A histochemical method was used for the detection of \g=D\5-3\g=b\-hydroxysteroiddehydrogenase activity in the adrenal glands, testes, ovaries and placentae of ferrets. The enzyme was demonstrated in the adrenocortical tissue, in the testicular Leydig cells of the testes, and in the granulosa lutein cells, the theca lutein cells and the theca interna of healthy and atretic follicles of the ovary. There was no enzyme activity in any part of the placenta, even when incubation was prolonged. All the tissues of the organs examined were active for the NAD diaphorase reaction. Lipid staining did not parallel the activity of \g=D\5-3\g=b\-hydroxysteroiddehydrogenase. The pattern of distribution of \g=D\5-3\g=b\-hydroxysteroiddehydrogenase activity resembles that seen in the guinea-pig, and differs from that seen in many other species\p=m-\inparticular the rabbit, another induced ovulator.

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Section: Introductionmentioning

confidence: 99%

5-3 -Hydroxysteroid Dehydrogenase Activity in the Steroid-Hormone Producing Organs of the Ferret (Mustela Putorius Furo)

Galil¹,

Deane²

1966

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“…In addition to aldosterone, the normally important adrenocortical hormones are corticosterone and hydrocortisone, and their respective ratios vary from species to species (Bush, 1953;Nelson, 1955) and possibly with the degree of cortical stimulation (Bradlow and Gallagher, 1957). The ratio of hydrocortisone to corticosterone (F:B ratio) may vary from less than 0.05 in rats and rabbits to greater than 20 in monkeys (Bush, 1953;Reif and Longwell, 1958;Dorfman, 1959) . Most species lie between these two extremes (Bush, 1953) .…”

Section: Introductionmentioning

confidence: 99%

Physiological Mammalogy

1963

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The first volume consists of two comprehensive articles dealing with the physiology of populations. Calhoun's "The Social Use of Space" presents many interesting new ideas on the behavior of animals in populations and the effects of grouping of individuals upon the physiology of the organism. Where many workers have thought of the experimental animal only as an individual apparently divorced from his environment and other members of the species, Calhoun points out the fallacy of this view in providing experimental data that demonstrate the effects of numbers of individuals on the behavior of each individual. Christian's article on population growth treats the problem largely from an ecological viewpoint in dealing with limiting factors of natural populations and population interrelationships. Volume II will consist of three contributions dealing with natural populations and their adaptations to stressful environments. Dr. Charles Kayser treats the mammalian phenomenon of hibernation as a mechanism for avoiding periods of unfavorable environment, and Dr. Robert Chew deals with water balance in desert rodents. Inasmuch as reproduction is considerably affected by the environment, it too can be considered a process modified by environmental stresses, and is discussed in the second volume. Subsequent volumes will include articles on such topics as temperature and metabolism, physiological genetics, photoperiod, and orientation by echolocation. The Editors will conclude the series with a summary article on the phylogeny of physiology. The Editors feel particularly fortunate in that they have received fine cooperation from outstanding authorities in the specific subject matter topics covered. It is the caliber of the individual author on which these volumes base their contribution to science; and while the Editors assume any responsibility for defects of organization or inadvertent errors, the credit for the success of the volumes, as a whole, rests on the indi^'idual contributors.

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Funktionsmorphologie des Interrenalorgans von Rana temporaria L.

Pehlemann

Hanke

1968

Zeitschrift f�r Zellforschung

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Biochemistry of the adrenocortical hormones

Cited by 5 publications

References 513 publications

5-3 -Hydroxysteroid Dehydrogenase Activity in the Steroid-Hormone Producing Organs of the Ferret (Mustela Putorius Furo)

5-3 -Hydroxysteroid Dehydrogenase Activity in the Steroid-Hormone Producing Organs of the Ferret (Mustela Putorius Furo)

Physiological Mammalogy

Funktionsmorphologie des Interrenalorgans von Rana temporaria L.

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