Biocompatibility and mineralization activity of modified glass ionomer cement in human dental pulp stem cells

Chumpraman, Apisit; Tannukit, Sissada; Chotigeat, Wilaiwan; Kedjarune‐Leggat, Ureporn

doi:10.1016/j.jds.2022.11.024

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…A study by Chumpraman and co-authors proved that including bioactive molecules in the composition of modified glass-ionomer cement leads to the proliferation of cells in stem cells from dental pulp and potentiates calcium deposition. This study discovered possibilities for investigated modifications of glassionomer cement and direct pulp capping (7).…”

Section: Discussionmentioning

confidence: 95%

A study of the cytotoxicity of resin-modified glass-ionomer cement

Kirilova

2024

MedInform

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Background. It is crucial to maintain the vitality of the dental pulp by using biologically tolerable materials when placed on dentin near the dental pulp. Calcium-hydroxide cement has been established as such a material.Resin-modified Glass-ionomer cement (RMGIC) is another group of materials. The results on the biological tolerance of different types are contradictory.Aim. Therefore, we conducted a study to compare the cytotoxicity of glass-ionomer cement available in powder and liquid packages with individual capsule doses on cell cultures. Material and methods.The materials used in this study are zink phosphate cement AdhesorTM Fine (GR.1), resinmodified glass-ionomer cement Fiji LC II (Gr.2) powder-liquid package; Fiji LC II (Gr3) individual capsules package, calcium-hydroxide cement Basic L (Gr.4). The study was conducted on human skin-muscle embryonic fibroblasts (diploid cells) cell cultures.Results. The study's results indicate that RMGIC Fuji LC II and calcium-hydroxide cement studies have approximately the same degree of relative growth on cell cultures. However, in powder-liquid packaging, the results deteriorate over time, while individual ones retain their qualities.Conclusions. The present study's limitation is that RMGIC packages influenced the materials' cytotoxicity degree.Individual capsules of RMGIC had a better degree of cytotoxicity close to the calcium-hydroxide cement. Further research is needed along these lines.

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Section: Discussionmentioning

confidence: 95%

A study of the cytotoxicity of resin-modified glass-ionomer cement

Kirilova

2024

MedInform

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“…It has been stated that Bio-GIC can be further developed as a bioactive material for dentin regeneration. 60…”

Section: Approaches To Improve Biocompatibilitymentioning

confidence: 99%

An overview to biocompatibility of resin based restorative materials

Avcılar,

Bakır,

Bakır

2023

JDSE

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Nowadays, resin based materials find a wide range of use in dentistry due to their aesthetic properties, mechanical durability and cost advantages. Dentistry materials; They can have an effect because they are in direct contact with various tissues such as gums, tongue, lips and cheeks, in addition to periodontium, pulp, dentin and enamel. It is important that resin materials produced with new technologies to be used in restorative dentistry not only have mechanical, physical, functional and aesthetic properties, but also be carefully evaluated in terms of biological compatibility. The purpose of this review is to review the basic concepts and methods related to biocompatibility, to present data from studies on the cytotoxicity of resin-based materials, and finally to make recommendations for clinical applications.

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