Biocompatibility of lipid microcylinders: effect on cell growth and antigen presentation in culture

Supramolecular organic nanotubes: how to utilize the inner nanospace and the outer space

“…99,100 The longterm release of a transforming growth factor-b (TGF) from the nanotube was employed in cell cultures for soft tissue regeneration. 101,102 About 10-12% of the TGF was released in the first 10 h at 37 C, and the rate of release changed depending on the temperature. Furthermore, Yager et al developed a controlled release system to tune the release rate of model drugs over a broad range of time (days to years).…”

Controllable biomolecule release from self-assembled organic nanotubes with asymmetric surfaces: pH and temperature dependence

“…On the other hand, self-assembled organic nanotubes 14 from the amphiphilic molecules have unique characteristics including tunable inner and outer surfaces, [15][16][17][18] controllable inner diameters, 17 thermoreversible formation and deformation, and high affinities to the bio-enviroment. [19][20][21][22][23][24][25] Those features have enabled us to achieve selective and effective encapsulation of nanoparticles, spherical proteins and double-strand DNAs into functionalized hollow cylinders of the organic nanotubes. 11c, 26 To date several research groups have reported the release phenomena in solutions of an encapsulated guest from the hollow cylinder of organic nanotubes.…”

Nanotubes Self-Assembled from Amphiphilic Molecules via Helical Intermediates

“…The application for lipid tubes that has been most well investigated in the literature is the use of tubes as delivery and controlled release agents of encapsulated materials. , The first practical work in determining the efficacy of lipid tubules as controlled release agents was conducted by Price et al, ,, who investigated the release of antibiofouling agents from metallized DC 8,9 PC tubes, the inorganic coating required to thermally, mechanically, and photochemically stabilize the tubes . Price and Patchan , internalized tetracycline within nickel and iron coated tubes, along with epoxy resin.…”