Biocompatible alkyne arms containing Schiff base fluorescence indicator for dual detection of Cd<sup>II</sup> and Pb<sup>II</sup> at physiological pH and its application to live cell imaging

Andrews, S. G. Jebastin; Silviya, S. Benita Jeba; Jeyanthi, Dharmaraj; Devi, E. Sathya; Jebaraj, J. Winfred; Balakrishnan, Chithiraivel

doi:10.1039/d0an00862a

Cited by 18 publications

(2 citation statements)

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“…[39][40][41][42] and pH indicators. [43][44][45] Schiff bases are compounds that are structurally similar to biological substances found in nature. They are simple to prepare and chemically modify, which allows for the design of the desired structural properties.…”

Section: Introductionmentioning

confidence: 99%

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

Sobczak,

Sierański,

Świątkowski

et al. 2023

CrystEngComm

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Section: Introductionmentioning

confidence: 99%

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

Sobczak,

Sierański,

Świątkowski

et al. 2023

CrystEngComm

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“…The normal range of lead (Pb) in the earth's crust is believed to be 15 mg/kg. Lead-nitrate was produced commercially in the 19th-century Lead poisoning, which is especially common in children, is still the most common disease caused by the environment in the United States and around the world 7 . According to current research, lead and its derivatives take part of the human body through wastewater and waste residue, causing hematopoiesis, neurological system, digestive system, and renal damage, as well as chronic poisoning 8 .…”

Section: Introductionmentioning

confidence: 99%

Fluorescent and Colorimetric Chemosensor for the Detection of Toxic Metal Ions of Mercury and Lead – A Mini Review

Tamizselvi¹,

Napoleon²

2022

ECS Trans.

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Variations in the predictable level of heavy metals ions have an uncompromising influence on living being and their surroundings. Real sample analysis was used to identify the heavy metal ions by using colorimetric and fluorescence techniques. The interaction of metal ions with the receptor has produced observable signals as measured by its photophysical changes. Nitrogen-containing heterocyclic compounds are the greatest weapons for identifying heavy metal ions, owing to their diverse reactivity, readily available substrate, and exquisite photophysical property. The main goal of this mini-review is to examine the current advancements in the structural analysis of nitrogen-containing heterocyclic compound-based fluorescence and colorimetric sensors. The interaction between receptor and metal by electron transfer mechanism and its wide applications have been developed and used for the sensing of heavy metal ions in the past ten years by various research groups about selectivity, sensitivity, reversibility, pH effect, stoichiometric ratio, binding constant, LOD values, and real-time applications.

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Influences of polarizability effect of alkyl group and homoring competition effect of substituents on the fluorescence emission spectra of salen‐type Schiff bases

Wei¹,

Cao²

2021

J of Physical Organic Chem

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To explore the effect of substituent attached to aromatic ring and the length of diamine chain in salen-type Schiff base molecules on the fluorescence emission spectra (FL em ), the FL em of 63 diamine-salicylaldehyde condensates in an ethanol solution were obtained. The influence of substituent electronic effects and chain lengths on the wavenumber (ν em ) of fluorescence emission wavelengths (λ em ) was subsequently studied. The results show that the length of the diamine chain in the target compound has an effect on the ν em , which can be quantified by the alkyl polarizability effect index (PEI), where compounds with alkyl of higher PEI have lower ν em . Second, the λ em of salen-type Schiff bases can be quantified by an equation of the seven parameters, PEI, σ(X) ─OH , σ(X) ─CH═N , σ ex CC X ð Þ ─OH , σ ex CC X ð Þ ─CH═N , Δσ 2 p and Δσ 2 m , form where the stability and predictive ability of the obtained equation was confirmed by leave-one-out cross validation. Lastly, it was observed that the influence on the λ em of substituent X attached to the aromatic ring is related to its position relative to OH or CH═N groups as reference, whose Hammett constants (σ(X) ─OH , σ(X) ─CH═N ) and the excited-state substituent constants (σ ex CC X ð Þ ─OH , σ ex CC X ð Þ ─CH═N ) of the substituents X with varying locating methods have different effects on the λ em ;and that there is a "homoring competition effect" of substituent.

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Biocompatible alkyne arms containing Schiff base fluorescence indicator for dual detection of Cd^II and Pb^II at physiological pH and its application to live cell imaging

Abstract: An alkyne arms containing salen-type Schiff base ligand L acts as a dual sensor for CdII and PbII with well-separated excitation and emission wavelengths. The ligand L has been utilized in cell imaging studies for both metal ions.

Cited by 18 publications

References 41 publications

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

Fluorescent and Colorimetric Chemosensor for the Detection of Toxic Metal Ions of Mercury and Lead – A Mini Review

Influences of polarizability effect of alkyl group and homoring competition effect of substituents on the fluorescence emission spectra of salen‐type Schiff bases

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Biocompatible alkyne arms containing Schiff base fluorescence indicator for dual detection of CdII and PbII at physiological pH and its application to live cell imaging

Abstract: An alkyne arms containing salen-type Schiff base ligand L acts as a dual sensor for CdII and PbII with well-separated excitation and emission wavelengths. The ligand L has been utilized in cell imaging studies for both metal ions.

Cited by 18 publications

References 41 publications

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

New Schiff base salts as sources of blue and green light in the solid state: the role of the anion and protonation

Fluorescent and Colorimetric Chemosensor for the Detection of Toxic Metal Ions of Mercury and Lead – A Mini Review

Influences of polarizability effect of alkyl group and homoring competition effect of substituents on the fluorescence emission spectra of salen‐type Schiff bases

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Biocompatible alkyne arms containing Schiff base fluorescence indicator for dual detection of Cd^II and Pb^II at physiological pH and its application to live cell imaging