Biocompatible ligands modulate nanozyme activity of CeO₂nanoparticles

Abstract

The diversity of catalytic activities and antioxidant properties of cerium oxide nanoparticles (CeO2 NPs) makes them promising materials for the theranostics of various diseases, especially those caused by disturbances in...

Gadolinium Doping Modulates the Enzyme-like Activity and Radical-Scavenging Properties of CeO2 Nanoparticles

“…A superoxide anion radical (•O 2 − ) is one of the primary ROS formed during free radical metabolism in living organisms. The main sources of •O 2 − in the body are mitochondria and enzymatic systems: NADPH oxidase, xanthine oxidase, lipoxygenase, and cyclooxygenase [74,[83][84][85]. The ability to catalyze the dismutation of superoxide anion radicals was among the first types of enzyme-like activity discovered in nanocrystalline CeO 2 [14,15,86,87].…”

Shaddock peel-loaded CeO2 composites with peroxidase-like activity for dye degradation and trace detection of ascorbic acid

“…Till now, numerous strategies have been developed to modulate the activities of nanoceria such as surface modification, 17,18 doping transition metals 19–23 and regulating morphology and size. 24,25 Zhao found that fluoride-capped nanoceria can significantly improve the oxidase-like activity of nanoceria, which stemmed from the increase of the concentration of Ce 3+ and the accompanying oxygen vacancies upon adding F − . 17 Guo showed that the peroxidase mimicking activity of nanoceria was significantly enhanced after Mn doping because of the surface oxygen (Oβ) and the synergistic effect between Ce and Mn.…”