Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering

Swetha, M.; Sahithi, Kolli; Moorthi, A.; Srinivasan, Narasimhan; Ramasamy, Kumarasamy; Selvamurugan, N.

doi:10.1016/j.ijbiomac.2010.03.015

Cited by 495 publications

(258 citation statements)

References 49 publications

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“…For example, extracellular cell matrix (ECM) components possess cell specific domains such as RGD (Arg-gly-Asp) sequence which help in cell attachment [101]. Therefore, natural polymer based coatings on implanted material enhance the interactions between the implant surface and surrounding tissue matrix, thereby expediting the regeneration of tissues [22].…”

Section: Natural Polymers Coatingsmentioning

confidence: 99%

Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications

Agarwal

Curtin²,

Duffy

et al. 2016

Materials Science and Engineering: C

773

363

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Magnesium (Mg) and its alloys have been extensively explored as potential biodegradable implant materials for orthopaedic applications (e.g. Fracture fixation). However, the rapid corrosion of Mg based alloys in physiological conditions has delayed their introduction for therapeutic applications to date. The present review focuses on corrosion, biocompatibility and surface modifications of biodegradable Mg alloys for orthopaedic applications. Initially, the corrosion behaviour of Mg alloys and the effect of alloying elements on corrosion and biocompatibility is discussed. Furthermore, the influence of polymeric deposit coatings, namely sol-gel, synthetic aliphatic polyesters and natural polymers on corrosion and biological performance of Mg and its alloy for orthopaedic applications are presented. It was found that inclusion of alloying elements such as Al, Mn, Ca, Zn and rare earth elements provides improved corrosion resistance to Mg alloys. It has been also observed that sol-gel and synthetic aliphatic polyesters based coatings exhibit improved corrosion resistance as compared to natural polymers, which has higher biocompatibility due to their biomimetic nature. It is concluded that, surface modification is a promising approach to improve the performance of Mg-based biomaterials for orthopaedic applications.

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Section: Natural Polymers Coatingsmentioning

confidence: 99%

Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications

Agarwal

Curtin²,

Duffy

et al. 2016

Materials Science and Engineering: C

773

363

View full text Add to dashboard Cite

show abstract

“…Different materials, such as natural/synthetic polymers, carbon nanotubes, hydroxyapatite (HAp), and silicates, have been used to design and process nanocomposites to meet the diverse needs of tissue engineering [111,[123][124][125]. Special attention has been given to the combination of biopolymers (i.e., proteins, polysaccharides, and glycosaminoglycans) with inorganic/ceramic fillers, which provide biomaterial composites with optimized properties [125].…”

Section: Biomaterials Scaffoldsmentioning

confidence: 99%

“…Special attention has been given to the combination of biopolymers (i.e., proteins, polysaccharides, and glycosaminoglycans) with inorganic/ceramic fillers, which provide biomaterial composites with optimized properties [125]. The natural tissue interface is a continuous gradient structure; thus, versatile biological composites are needed to create suitable biomimetic engineered grafts for interfacial tissue engineering.…”

Section: Biomaterials Scaffoldsmentioning

confidence: 99%

Recent biomedical applications of bio-sourced materials

Elbaz

Gao

et al. 2018

Bio-des. Manuf.

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Natural anisotropic nanostructures occurring in several organisms have gained more and more attention because of their obvious advantages in sensitivity, stability, security, miniaturization, portability, online use, and remote monitoring. Due to the development of research on nature-inspired bionic structures and the demand for highly efficient, low-cost microfabrication techniques, an understanding of and the ability to replicate the mechanism of structural coloration have become increasingly significant. These sophisticated structures have many unique functions and are used in many applications. Many sensors have been proposed based on their novel structures and unique optical properties. Several of these bio-inspired sensors have been used for infrared radiation/thermal, pH, and vapor techniques, among others, and have been discussed in detail, with an intense focus on several biomedical applications. However, many applications have yet to be discovered. In this review, we will describe these nanostructured materials based on their sources in nature and various structures, such as layered, hierarchical, and helical structures. In addition, we discuss the functions endowed by these structures, such as superhydrophobicity, adhesion, and high strength, enabling them to be employed in a number of applications in biomedical fields, including cell cultivation, biosensors, and tissue engineering.

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“…This new generation of biomaterials combines with bioactive properties that resemble the natural function of bone, triggering tissue regeneration mechanisms in vivo [18,19]. Biocomposites HAp-biopolymers that often closely resemble the position and structure of mineralized tissues provide excellent mechanical properties and favorable biological properties, proving to be an ideal candidate for tissue engineering as well as orthopedic and dental applications [20].…”

Section: Introductionmentioning

confidence: 99%

Tuned Hydroxyapatite Materials for Biomedical Applications

Vieira¹,

Vieira²,

Silva³

et al. 2018

Biomaterials - Physics and Chemistry - New Edition

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Hydroxyapatite stands out between biomaterials due to its properties of osteoconduction and osteoinduction, being adequate to be used in bone grafts. The high stability and flexibility of the structure allows for several biomedical applications, for example, the use as polysaccharide based on the scaffold formulations and the cationic substitutions occurring through the doping of the material using metals, which may enhance biological characteristics, such as improving the action of combating bacterial infections in situ. This study was a research of articles and patents, without and with time restriction (2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016)(2017), which contain information about hydroxyapatite in the tissue engineering, biomedical, doped with cerium and its properties of antibacterial activity.There were also searches of products and companies that commercialize these types of materials aimed at tissue engineering area. Scopus was used for searched of articles and were EPO, USPTO, and INPI used for patents, and to search for products and companies were used search engines. Few papers were found to associate all the keywords, but the ones found are recent works, thus showing a new area with potential to be investigated.

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Biocomposites containing natural polymers and hydroxyapatite for bone tissue engineering

Cited by 495 publications

References 49 publications

Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications

Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications

Recent biomedical applications of bio-sourced materials

Tuned Hydroxyapatite Materials for Biomedical Applications

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