Biocompounds from rapeseed oil industry co‐stream as active ingredients for skin care applications

Abstract

Abstract:OBJECTIVE: Despite the great number of substances produced by the skin care industry, very few of them seem to truly have an effect on the skin. Therefore, given the social implications surrounding physical appearance, the search for new bioactive compounds to prevent or attenuate skin aging and enhance self-image is a priority of current research. In this context, being rich in valuable compounds such as proteins, phenolics, lipids and vitamins, this study is focused in the potential activity of rapeseed press cake hydrolyzates to be used as raw materials for skin care applications. METHODS:In this study, the protein-rich press residue from the rapeseed oil industry was converted enzymatically into short-chain biologically active peptides using four protease products with varying substrate specificity -Alcalase 2.4L FG, Protex 6L, Protamex and Corolase 7089. The antioxidant, anti-wrinkle and anti-inflammatory activity of the obtained hydrolyzates were evaluated in vitro while their biocompatibility with human skin firoblasts was tested. RESULTS:All hydrolyzates were biocompatible with skin fibroblasts after 24 h of exposure, while the non-hydrolyzed extract induced cell toxicity. Alcalase 2,4L FG and Protex 6L -obtained hydrolyzates were the most promising extracts showing improved bioactivities suitable for skin anti-ageing formulations, namely anti-oxidant activity, inhibiting approximately 80% cellular reactive oxidative species, anti-inflammatory and anti-wrinkle properties, inhibiting around 36% of myeloperoxidase activity and over 83% of elastase activity. CONCLUSION:The enzymatic technology applied to the rapeseed oil industry co-stream results in the release of bioactive compounds suitable for skin care applications.

Rapeseed (Brassica napus): Processing, Utilization, and Genetic Improvement

“…Rapeseed meals could also be used for fabrication of cosmetics. The application of rapeseed hydrolysates in producing skin anti-aging formulations was reported by Rivera et al [221], who converted the rapeseed protein-rich residues to biologically active peptides by using enzymes. After 24 h of exposure, hydrolysates were biocompatible with skin, in contrast to the non-hydrolyzed extract, which led to cells' toxicity.…”

Kombucha fermentation as a modern way of processing vineyard by‐products into cosmetic raw materials

“…The use of components from natural sources, such as agricultural by-products, not only supports the development of a value-added product (because of its sustainability) but also creates products that are more attractive to consumers. Thus, grape processing by-products were investigated for their potential use in cosmetic applications [14,15] including shower gels [13], face moisturizing creams [16], serums [17] and sunscreens [18].…”

Biotransformation technology and high-value application of rapeseed meal: a review

“…Polysaccharides, which are mainly formed from the polymerization of galactose, arabinose, and glucose, exert a strong scavenging effect on superoxide and hydroxyl radicals (Zhu and Wu 2009 ). Rivera et al ( 2015 ) hydrolysed RSM using protease to obtain short-chain bioactive peptides that displayed good antioxidant, anti- wrinkle, and anti-inflammatory activities; the peptides were safe, nontoxic, and compatible with skin fibroblasts, thereby showing good application potential in skin care. Paciorek-Sadowska et al ( 2019 ) used rapeseed cake as a biofiller in the production of rigid polyurethane–polyisocyanurate foams, which are considered the best polymer materials for heat insulation.…”