Bioconcentration and excretion of fenitrothion in the brain of the eel (Anguilla anguilla)

Abstract

The bioconcentration of fenitrothion in the brain of the european eel (Anguilla anguilla) and its posterior elimination have been studied. Animals were exposed to a sublethal concentration of fenitrothion (0.04 mg/L) for 96 hours in a flow-through test system. After this pesticide exposure, animals were transferred to clean water for 72 hours more. Bioconcentration and elimination processes of fenitrothion were studied in blood and brain. This insecticide showed a strong tendency to bioconcentrate into selected tissues. A steady-state was observed in blood in few hours. Highest accumulation was detected in brain, where any steady-state could be observed. Elimination started rapidly from both tissues when a recovery period was allowed. Elimination kinetics were adjusted to one-compartment model. K2 of 0.015 and 0.044 hr-1 were calculated for fenitrothion in blood and brain. These K2 values were related with a relatively short half-live of fenitrothion in the analyzed tissues; probably due to the low biotransformation rate of this toxicant in the european eel. That fact would protect the animals against many biotransformation products even more toxic than the parent fenitrothion.

The development and application of a novel hazard scoring tool for assessing impacts of cosmetic ingredients on aquatic ecosystems: A case study of rinse‐off cosmetics

“…According to the scientific literature, organic UV filters are proven to be bioaccumulative (Lozano et al, 2020). Organic UV filters are highly hydrophobic (high log K ow ), resulting in bioaccumulation in aquatic species (e.g., crustaceans, mollusks, fish, and mammals; Lozano et al, 2020), and the bioconcentration varies among species, being higher in species with a high body content of lipids (Gago‐Ferrero et al, 2015; Sancho et al, 1997). Although biomagnification has been poorly documented, fish species at higher trophic positions presented higher concentrations of UV filters than small fish (at lower trophic positions), suggesting the occurrence of biomagnification (Lozano et al, 2020).…”