Biodegradability and biocompatibility: Advancements in synthetic surfactants

Chowdhury, Suman; Rakshit, Atanu; Acharjee, Animesh; Saha, Bidyut

doi:10.1016/j.molliq.2020.115105

Cited by 52 publications

(20 citation statements)

References 85 publications

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“…In addition, dropping off surfactants to biological treatment facilities can cause serious problems in the operation of activated sludge, in particular, the inhibition of protein structures of microorganisms [2,10,11]. Surfactants also cause increased foaming and are adsorbed on bacterial cells, which negatively affects the biodegradability of wastewater components [12,13].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Kinetic Regularities of the Process of Biodegradation of Betaine Surfactant by Bacteria of the Genus Pseudomonas

et al. 2021

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Surfactants are extremely common organic compounds that enter the environment in large quantities in the form of household and industrial wastewater. The toxicity of surfactants for biological systems, the high concentration of substances and the duration of the bioremediation process of polluted ecosystems requires improving the biotechnology of microbial wastewater treatment for surfactants. The purpose of this work is to study the kinetic laws of the reaction of the biological decomposition of betaine surfactants. Pseudomonas bacteria were used as bio-destructors of the surfactants. Kinetic data were obtained to create the possibility of further optimization of research on the biodegradation of toxic organic substances. The strains that were promising destructors of cocamidopropylbetaine were selected. The toxicity of high concentrations of surfactants in relation to microorganisms of the genus Pseudomonas was proven. Safe values of the surfactant concentration for conducting biodegradation tests were found. A kinetic model of the biodestructive process was constructed. It proves that the processes of biodegradation are described by a kinetic equation of the first order. With the derived equation, it is possible to determine the time interval of biodegradation of cocamidopropylbetaine to the specified values by means of mathematical calculations.

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Section: Introductionmentioning

confidence: 99%

Investigation of the Kinetic Regularities of the Process of Biodegradation of Betaine Surfactant by Bacteria of the Genus Pseudomonas

et al. 2021

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“…It was later followed by that of alkyl poly-oxyethylene glycol mono-ethers ( Schick, 1963 ), and by species of the like. The same holds for the synthesis of surfactants from natural sources ( Mäki‐Arvela et al, 2007 ; Kraus and Lee, 2012 ; Chowdhury et al, 2020 ).…”

Section: Introductionmentioning

confidence: 80%

Surface Activity and Efficiency of Cat-Anionic Surfactant Mixtures

Mesa

Risuleo

2021

Front. Chem.

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The surface activity of surfactant mixtures is critically analyzed. Cat-anionic systems, in which two ionic species are mixed in non-stoichiometric ratios, are considered. With respect to the solution behavior, where a substantial decrease of cmc is met compared to the pure components, a moderate effect on surface tension, γ, occurs. Compared to the pure species, the decrease of surface tension for such mixtures is not significant, and no clear dependence on the mole fraction anionic/cationic is met. The surface tension is grossly constant in the whole concentration range. Conversely, the interaction parameter for surfaces, βsurf (calculated by the regular solution theory), is more negative than that for micelle formation, βmic. This fact suggests that the desolvation of polar heads of the two species at interfaces is largely different. Very presumably, the underlying rationale finds origin in the sizes and solvation of both polar head groups.

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“…From the viewpoint of safety of drug delivery systems, biodegradability and biocompatibility are of key importance [25]. Hence, much attention is paid to the design of surfactants satisfying these criteria.…”

Section: Nanocontainers Based On Biodegradable Surfactantsmentioning

confidence: 99%

Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability

et al. 2021

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This review focuses on key topics in the field of drug delivery related to the design of nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability, low toxicity, and the ability to overcome biological barriers. For these reasons, much attention is paid to the amphiphile-based carriers composed of natural building blocks, lipids, and their structural analogues and synthetic surfactants that are capable of self-assembly with the formation of a variety of supramolecular aggregates. The latter are dynamic structures that can be used as nanocontainers for hydrophobic drugs to increase their solubility and bioavailability. In this section, biodegradable cationic surfactants bearing cleavable fragments are discussed, with ester- and carbamate-containing analogs, as well as amino acid derivatives received special attention. Drug delivery through the biological barriers is a challenging task, which is highlighted by the example of transdermal method of drug administration. In this paper, nonionic surfactants are primarily discussed, including their application for the fabrication of nanocarriers, their surfactant-skin interactions, the mechanisms of modulating their permeability, and the factors controlling drug encapsulation, release, and targeted delivery. Different types of nanocarriers are covered, including niosomes, transfersomes, invasomes and chitosomes, with their morphological specificity, beneficial characteristics and limitations discussed.

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Biodegradability and biocompatibility: Advancements in synthetic surfactants

Cited by 52 publications

References 85 publications

Investigation of the Kinetic Regularities of the Process of Biodegradation of Betaine Surfactant by Bacteria of the Genus Pseudomonas

Investigation of the Kinetic Regularities of the Process of Biodegradation of Betaine Surfactant by Bacteria of the Genus Pseudomonas

Surface Activity and Efficiency of Cat-Anionic Surfactant Mixtures

Self-Assembling Drug Formulations with Tunable Permeability and Biodegradability

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