Biodegradable batteries with immobilized electrolyte for transient MEMS

She, Didi; Tsang, Melissa; Allen, Mark G.

doi:10.1007/s10544-019-0377-x

Cited by 26 publications

(25 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An energy density of 694 Wh kg −1 with a 0.02 cm 3 total volume is achieved . As shown in Figure e, the introduction of dry electrolyte (PCL films) with preloaded salts enables water activated Mg–Fe batteries with prolonged storage time and allows performance relatively independent of the external biofluids environment …”

Section: Energy Storage Systemsmentioning

confidence: 98%

“…); polymers acting as dielectrics, electrolytes or encapsulations (poly lactic‐ co ‐glycolic acid (PLGA), polycaprolactone (PCL), polyanhydride, alginate, etc. ); and semiconductors (silicon (Si), silicon germanium alloy (SiGe), indium–gallium–zinc‐oxide (IGZO), etc.) which act as key components for diodes or transistors …”

Section: Materials and Structural Strategies Of Power Devicesmentioning

confidence: 99%

Section: Energy Storage Systemsmentioning

confidence: 99%

“…Batteries with all dissolvable materials have been proposed to build fully degradable systems. Materials candidates include biodegradable metals (Mg, Zn, Fe, tungsten (W), Mo et al), dissolvable oxides (MoO 3 ), and biodegradable polymers or hydrogels (e.g., PLGA, alginate) as the electrolyte and encapsulation materials. A fully biodegradable Mg–MoO 3 battery reported by Huang et al appears in Figure c .…”

Section: Energy Storage Systemsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Materials Strategies and Device Architectures of Emerging Power Supply Devices for Implantable Bioelectronics

Huang

Wang

et al. 2019

Small

108

View full text Add to dashboard Cite

Implantable bioelectronics represent an emerging technology that can be integrated into the human body for diagnostic and therapeutic functions. Power supply devices are an essential component of bioelectronics to ensure their robust performance. However, conventional power sources are usually bulky, rigid, and potentially contain hazardous constituent materials. The fact that biological organisms are soft, curvilinear, and have limited accommodation space poses new challenges for power supply systems to minimize the interface mismatch and still offer sufficient power to meet clinical‐grade applications. Here, recent advances in state‐of‐the‐art nonconventional power options for implantable electronics, specifically, miniaturized, flexible, or biodegradable power systems are reviewed. Material strategies and architectural design of a broad array of power devices are discussed, including energy storage systems (batteries and supercapacitors), power devices which harvest sources from the human body (biofuel cells, devices utilizing biopotentials, piezoelectric harvesters, triboelectric devices, and thermoelectric devices), and energy transfer devices which utilize sources in the surrounding environment (ultrasonic energy harvesters, inductive coupling/radiofrequency energy harvesters, and photovoltaic devices). Finally, future challenges and perspectives are given.

show abstract

Section: Energy Storage Systemsmentioning

confidence: 98%

Section: Materials and Structural Strategies Of Power Devicesmentioning

confidence: 99%

Section: Energy Storage Systemsmentioning

confidence: 99%

Section: Energy Storage Systemsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Materials Strategies and Device Architectures of Emerging Power Supply Devices for Implantable Bioelectronics

Huang

Wang

et al. 2019

Small

108

View full text Add to dashboard Cite

show abstract

Inkjet Printing of Bioresorbable Materials for Manufacturing Transient Microelectronic Devices

et al. 2020

View full text Add to dashboard Cite

Herein, the inkjet printing of bioresorbable materials tuned to function as electrode, dielectric, and semiconductor layers is reported, thereby developing multilayered microelectronic devices such as capacitors and thin‐film transistors, potentially applicable to address specific medical needs. Polymers and natural materials, e.g., poly(3,4‐ethylenedioxythiophene)‐poly(styrenesulfonate), shellac, and β‐carotene, indigo inks are implemented using jettable formulations, that are either commercially procured or self‐formulated, designed explicitly to deposit fundamental layers for capacitors and transistors. Several parameters are evaluated and adjusted to precisely define a layer's thickness, topology, and geometry, matching with the properties of a fully biodegradable Ormocere substrate, explicitly developed for the specific biological applications. Furthermore, these parameters support in acquiring the intended electrical properties of layers, i.e., conductivity, insulation, semiconductivity, capacitance, and current versus voltage characteristics. The entire manufacturing process of devices is accomplished on the Ormocere substrate under ambient conditions and below 60 °C. The results exhibit that the electrical characteristics of the printed functional layers and devices show direct influence to the physical geometry of the printed features. A fully printed capacitor demonstrates capacitance of 1 nF cm−2, whereas transistors show p‐type and n‐type characteristics with current 0.18–5 μA and mobility 6 × 10−4–7 × 10−2 cm2 V−1 s−1.

show abstract

Engineering Materials for Neurotechnology

Ghezzi

2023

Adv Eng Mater

View full text Add to dashboard Cite

A crucial issue for a neural interface is the chronic foreign body reaction (FBR) upon implantation. [1][2][3] Avoiding the FBR, or at least reducing its severity, is necessary to preserve the long-term functioning of neural interfaces. [4][5][6] Yet, this is still an open research question. The FBR is traditionally described as a passive barrier encapsulating the device, altering the neural interface, and impairing implant-to-cell communication. [2,7,8] Besides acting as a passive insulating barrier, soluble factors released during the inflammatory and fibrotic process can accelerate device degradation and electrode corrosion. [9] The FBR is inevitable whenever any material becomes in contact with body fluids. [10] In contrast, materials engineering and advanced fabrication processes can minimize its severity, for example, by improving the mechanical compliance of the implant, decreasing the device size, and reducing implantation and chronic trauma. [3] One of the most common limitations of neural interfaces is the mechanical mismatch between the stiff neural implant and the soft neural tissue. This mismatch intensifies the neural damage and FBR caused by insertion, compression, and motion. [11] The neural tissue is curved, soft, dynamic, and subject to deformations caused, for example, by blood pulsation, respiratory pressure, and natural body movements. [11,12] By contrast, most neural interfaces are static and struggle to conform to neural tissue in static and dynamic conditions. A large body of research in neural interfaces addresses this issue using flexible, conformable, or stretchable neural interfaces (Figure 1).Polyimide (PI), parylene-C, and SU-8 are widely used materials in flexible neural interfaces. [13][14][15][16][17][18][19][20][21][22] The advantages of these materials are their biochemical and thermal stability, and their compatibility with clean-room microfabrication processes. [23][24][25] However, they exhibit high Young's modulus (GPa range) and limited elastic deformation (<3%). [26] Ultra-thin neural interfaces made of these materials still reach low bending stiffness if sufficiently thin (<15 μm) despite the high Young's modulus. [27] They can conform to a cylindrical body such as a nerve or a smooth brain surface (Figure 1a), thus reducing the FBR severity. [23] Moreover, ultra-thin neural interfaces with a small cross-sectional area also can minimize tissue damage during penetration (Figure 1b). [22,24,28] Conformability to cylindrical or smooth surfaces is sufficient in rodents, but more is needed for large and complex surfaces with gyri, like in primates, where spherical conformability is required. Because of the limited elastic deformation, conformability to convoluted surfaces is difficult to achieve with these materials. Compliance with neural macro-and micro-movements is also reduced. [26] Elastomers exhibit a lower Young's modulus of at least three orders of magnitude (MPa range) and a much broader elastic regime under strain (>20%). Bending stiffness is influenced by both thick...

show abstract

Biodegradable batteries with immobilized electrolyte for transient MEMS

Cited by 26 publications

References 32 publications

Materials Strategies and Device Architectures of Emerging Power Supply Devices for Implantable Bioelectronics

Materials Strategies and Device Architectures of Emerging Power Supply Devices for Implantable Bioelectronics

Inkjet Printing of Bioresorbable Materials for Manufacturing Transient Microelectronic Devices

Engineering Materials for Neurotechnology

Contact Info

Product

Resources

About