Biodegradable PLLA/PLGA microspheres/collagen composites for continuous soft tissue augmentation

Li, Xuan; Liao, Xiangyi; Jia, Zhenzhen; Liu, Shuaiyin; Li, Ping; Li, Li; Zhang, Wei; Niu, Xufeng; Fan, Yubo

doi:10.1016/j.compositesb.2024.111603

Composites Part B: Engineering

2024

DOI: 10.1016/j.compositesb.2024.111603

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Biodegradable PLLA/PLGA microspheres/collagen composites for continuous soft tissue augmentation

Xuan Li,

Xiangyi Liao,

Zhenzhen Jia

et al.

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Cited by 3 publications

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Theoretical Analysis of Self-Shrinkage Spheroidization of Irregular Degradable Polymer Powder under Thermodynamic Nonequilibrium State

Shuai,

Yang,

et al. 2024

Additive Manufacturing Frontiers

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Theoretical Analysis of Self-Shrinkage Spheroidization of Irregular Degradable Polymer Powder under Thermodynamic Nonequilibrium State

Shuai,

Yang,

et al. 2024

Additive Manufacturing Frontiers

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Composite scaffolds based on egg membrane and eggshell-derived inorganic particles promote soft and hard tissue repair

Yuan,

Wu,

et al. 2025

Composites Part B: Engineering

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Poly-d,l-lactic Acid (PDLLA) Application in Dermatology: A Literature Review

Lee,

Chan,

Lee

et al. 2024

Polymers

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Poly-d,l-lactic acid (PDLLA) is a biodegradable and biocompatible polymer that has garnered significant attention in dermatology due to its unique properties and versatile applications. This literature review offers a comprehensive analysis of PDLLA’s roles in various dermatological conditions and wound-healing applications. PDLLA demonstrates significant benefits in enhancing skin elasticity and firmness, reducing wrinkles, and promoting tissue regeneration and scar remodeling. Its biodegradable properties render it highly suitable for soft tissue augmentation, including facial and breast reconstruction. We discuss the critical importance of understanding PDLLA’s physical and chemical characteristics to optimize its performance and safety, with a focus on how nano- and micro-particulate systems can improve delivery and stability. While potential complications, such as granuloma formation and non-inflammatory nodules, are highlighted, effective monitoring and early intervention strategies are essential. PDLLA’s applications extend beyond dermatology into orthopedics and drug delivery, owing to its superior mechanical stability and biocompatibility. This review underscores the need for ongoing research to fully elucidate the mechanisms of PDLLA and to maximize its therapeutic potential across diverse medical fields.

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Biodegradable PLLA/PLGA microspheres/collagen composites for continuous soft tissue augmentation

Cited by 3 publications

References 53 publications

Theoretical Analysis of Self-Shrinkage Spheroidization of Irregular Degradable Polymer Powder under Thermodynamic Nonequilibrium State

Theoretical Analysis of Self-Shrinkage Spheroidization of Irregular Degradable Polymer Powder under Thermodynamic Nonequilibrium State

Composite scaffolds based on egg membrane and eggshell-derived inorganic particles promote soft and hard tissue repair

Poly-d,l-lactic Acid (PDLLA) Application in Dermatology: A Literature Review

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