Biodegradable Polylactide‐Based Composites

Abstract

The aim of this chapter is to introduce to the use and possible applications of polylactide-based composites. Polylactides are biodegradable aliphatic polyesters, which are widely used in medical and ecological-friendly fields. First of all, a deep description of main characteristics of polylactides is shown. This chapter summarizes many concepts, which comprehend a general view of polylactide biopolymers such as synthesis and structures, physical-chemical and mechanical characterization and possible applications of final products. Then, an overview of composites based on polylactides and their benefits compared with bare polylactides are described.

Engineering 3D printed bioactive composite scaffolds based on the combination of aliphatic polyester and calcium phosphates for bone tissue regeneration

“…Due to the lower Ca/P ratio, TCP biodegradation process occurs 3 to 12 times faster than HA. Nevertheless, crystallinity degree, porosity, and surface area also play a significant role in biodegradation kinetics [13,14,18]. Recent advances using PLA/HA and PLA/TCP combined with FFF technologies, become possible to address some of the major demands of the PLA scaffolds, particularly the improvement in biocompatibility, mechanical properties, and production of the well-controlled porous structure.…”

Review on Additives in Hydrogels for 3D Bioprinting of Regenerative Medicine: From Mechanism to Methodology

“…printing technology and subsequently added polydopamine-coated BaSO4 particles within the scaffolds and adsorbed levofloxacin to impart antimicrobial properties to the scaffolds. Inorganic particle enhancers such as BaSO4 particles can improve the mechanical properties of the polymer and impart additional specific properties to the scaffold [140]. Polydopamine is an adhesive that often acts as a substrate coating to be conjugated with biologically active materials, e.g.…”

Crystallization Behavior and Mechanical Properties of Poly(ε-caprolactone) Reinforced with Barium Sulfate Submicron Particles

“…For instance, barium sulfate as an inorganic reinforcement has been already reported to be used with various polymer matrices such as polyethylene, polypropylene and poly(lactic acid); performance was reported to be reduced at large filler contents [ 23 , 24 , 25 , 26 ]. The fail in mechanical properties is often explained in terms of poor compatibility of the matrix–reinforcement interface [ 27 ]. In the particular case of PCL, a number of authors have demonstrated poor compatibility with other fillers [ 28 , 29 , 30 ].…”