2014
DOI: 10.14345/ceth.14015
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Biodegradable Polymer-Based Sirolimus Coating Stent in a Porcine Coronary Restenosis Model

Abstract: Animal preparation and stent implantation The animal study was approved by the Ethics Committee of Chonnam National University Medical School and Chonnam National University Hospital (CNU IACUC-H-2013-36), and conformed to the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health (NIH Publication No. 85-23, revised 1996). Study animals were castrated male pigs weighing 20-25 kg. To prevent acute thrombosis after stenting, premedication with aspirin 100 mg and clopid… Show more

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Cited by 4 publications
(4 citation statements)
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“…The procedure for coronary stenting was conducted as described previously. 9) The stent was deployed by inflating the balloon (3×20 mm), and the resulting stent-to-coronary artery ratio was 1.3:1. The diameter of the implanted coronary stent (stent-to-artery ratio) was adjusted with reference to the 7 F guiding catheter diameter (2.31 mm).…”
Section: Methodsmentioning
confidence: 99%
“…The procedure for coronary stenting was conducted as described previously. 9) The stent was deployed by inflating the balloon (3×20 mm), and the resulting stent-to-coronary artery ratio was 1.3:1. The diameter of the implanted coronary stent (stent-to-artery ratio) was adjusted with reference to the 7 F guiding catheter diameter (2.31 mm).…”
Section: Methodsmentioning
confidence: 99%
“…In a previous study comparing SES with PLA (SEP) and biolimus A9-eluting stents with PLA (BEP), SEP was not inferior to commercial BEP [17]. The main difference between the previous study using SEP and this study using SES is the addition of the antioxidant ALA to decrease the side effects of the sirolimus.…”
Section: Micro-ct Analysismentioning
confidence: 73%
“…The animal experiment for coronary stenting was conducted as described previously [17]. The stented pigs underwent follow-up angiography after 4 weeks.…”
Section: Animal Preparation and Stent Implantationmentioning
confidence: 99%
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