Biodegradable shape-memory block co-polymers for fast self-expandable stents

Liu, Xue; Dai, Shiyao; Li, Zhi

doi:10.1016/j.biomaterials.2010.07.043

Cited by 195 publications

(152 citation statements)

References 30 publications

Supporting

Mentioning

145

Contrasting

Unclassified

Order By: Relevance

“…13,14 Besides, shape memory polyurethane (SMPU) also has a wide range of applications in the biomedical field. 15,16 For example, using the shape memory effect of polyurethane based on poly(ε-caprolactone) (PCLU), Li 15 prepared fast self-expandable stents which could be used in tissue engineering. Betz reported available commercially polyetherurethanes (PEU) which is used in artificial hearts and pacemaker leads.…”

Section: ■ Introductionmentioning

confidence: 99%

Design of Triple-Shape Memory Polyurethane with Photo-cross-linking of Cinnamon Groups

Wang

Yang

Chen

et al. 2013

ACS Appl. Mater. Interfaces

105

View full text Add to dashboard Cite

A triple-shape memory polyurethane (TSMPU) with poly(ε-caprolactone) -diols (PCL-diols) as the soft segments and diphenyl methane diisocyanate (MDI), N,N-bis (2-hydroxyethyl) cinnamamide (BHECA) as the hard segments was synthesized via simple photo-crosslinking of cinnamon groups irradiated under λ > 280 nm ultraviolet (UV) light. Fourier transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance ( 1 H-NMR) and ultraviolet-visible absorption spectrum (UV−vis) confirmed the chemical structure of the material. Differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA) results demonstrated that the photocrosslinked polymer possessed two transition temperatures, one is due to the melting point of the soft segment PCL-diols, and the other is due to the glass transition temperature. All these contributed to the cross-linked structure of the hard segments and resulted in an excellent triple-shape memory effect. Alamar blue assay showed that the material has good non-cytotoxicity and can be potentially used in biomaterial devices.

show abstract

Section: ■ Introductionmentioning

confidence: 99%

Design of Triple-Shape Memory Polyurethane with Photo-cross-linking of Cinnamon Groups

Wang

Yang

Chen

et al. 2013

ACS Appl. Mater. Interfaces

105

View full text Add to dashboard Cite

show abstract

“…If the viscoelastic polymers are quickly increased, the rearranging time of the chains are shorter so that they become brittle; on the other hand, if they are slowly increased, the chains are rearranged so that they can be easily deformed. The physiochemical characteristics of the commercial biodegradable polymers are shown in Table 2 as follows [32][33][34][35][36][37][38][39][40][41][42][43][44][45][46]. Also, the glass transition temperature (T g ), an important physical characteristics in the polymers, was summarized.…”

Section: Polymer Mechanical Propertymentioning

confidence: 99%

Biodegradable stent

Kwon¹,

Kim²,

Kim³

et al. 2012

JBiSE

View full text Add to dashboard Cite

The bare metal stent (BMS) used in the blood vessel caused the restenosis after the operation due to formation and proliferation of neointimal. Recently, as a method to overcome the problems of BMS, drug eluting stent (DES) is developed and being applied to human body which has drug reducing restenosis applied on the metal surface. DES has the advantage of greatly reducing the restenosis after the operation; however, metal stent remains in the body after the drug is released causing issues such as late thrombosis and restenosis so that currently the attention is increasing for biodegradable materials that reduce restenosis and thrombosis by degrading as a certain amount of time passes after the drug is released by the stent material. In this review, the study trend of biodegradable stent will be explained.

show abstract

“…In addition, SMP-based biodegradable self-expanding and drug eluting stents (Wache, 2003;Xue, 2010;Yakacki, 2007), biodegradable self-deployable intragastric implants for treating obesity (Klausner, 2003;Pagano & Serezin, 2009), self-fitting vascular and coronary grafts (Sokolowski, 2007), patient-specific customized orthopedic devices (Sokolowski, 2007), tissue engineering scaffolds (Cui, 2011;Filion, 2011;Neuss, 2009;Xu & Song, 2010), and dynamic cell culture substrates (Davis, 2011) have also been explored. One of the most studied biomedical SMPs is cold hibernated elastic memory (CHEM)-processed polyurethane foams for endovascular treatment of aneurysm in animals (Metcalfe, 2003).…”

Section: Biomedical Smps: Applications and Challengesmentioning

confidence: 99%