Biodegradation and speciation of roxarsone in an anaerobic granular sludge system and its impacts

Zhang, Feifei; Wang, Wei; Yuan, Shuai; Hu, Zhenhu

doi:10.1016/j.jhazmat.2014.07.047

Cited by 58 publications

(25 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As animal feed additives, organic arsenic compounds including roxarsone (3-nitro-4-hydroxy benzene arsenic acid, ROX) and arsanilic acid (4-aminophenylarsonic acid, ASA) have been extensively used in the feed of broiler chickens and pigs to improve feed efficiency and prevent disease [1,2] of ASA and ROX for use as animal feed additives are in a range of 50.0-100.0 mg/kg for pigs and 20.0-50.0 mg/kg for broiler chickens [1,2]. More than 1 million kilograms of ASA and ROX are consumed every year in the United States, and more was consumed in China and other developing countries [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…It has been reported in a study in China that the content of arsenic in the pig manure and chicken litter were 89.3 and 21.6 mg/kg, respectively [5]. Organic arsenic compounds are transformed into inorganic arsenic compounds through both biotic and abiotic pathways [2,6,7]. Under anaerobic conditions, organic arsenic compounds were slowly degraded into inorganic arsenic compounds, including arsenite (As(III)) and arsenate (As(V)), and As(III) was the main species [2,[8][9][10].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Precipitation of organic arsenic compounds and their degradation products during struvite formation

Lin

Yuan

Wang

et al. 2016

Journal of Hazardous Materials

Self Cite

View full text Add to dashboard Cite

Roxarsone (ROX) and arsanilic acid (ASA) have been extensively used as organoarsenic animal feed additives. Organic arsenic compounds and their degradation products, arsenate (As(V)) and arsenite (As(III)), exist in the effluent from anaerobic reactors treating animal manure contaminated by ROX or ASA with ammonium (NH4(+)-N) and phosphate (PO4(3-)-P) together. Therefore, arsenic species in the effluent might be involved in the struvite formation process. In this study, the involvement of organic arsenic compounds and their degradation products As(V) and As(III) in the struvite crystallization was investigated. The results demonstrated that arsenic compounds did not substantially affect the PO4(3-)-P recovery, but confirmed the precipitation of arsenic during struvite formation. The precipitation of arsenic compounds in struvite was considerably affected by a solution pH from 9.0 to 11.0. With an increase in pH, the content of ASA and ROX in the precipitation decreased, but the contents of As(III) and As(V) increased. In addition, the arsenic content of As(V) in the struvite was higher than that of As(III), ASA and ROX. The results indicated that the struvite could be contaminated when the solution contains arsenic species, but that could be minimized by controlling the solution pH and maintaining anaerobic conditions during struvite formation.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Precipitation of organic arsenic compounds and their degradation products during struvite formation

Lin

Yuan

Wang

et al. 2016

Journal of Hazardous Materials

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our results, showing a better roxarsone degradation in the microcosms including nutrients supports the reports of these authors. Nevertheless, Liu et al (2014) reported that during nitrogen removal from wastewater the transformation of roxarsone is minimal at the beginning but it was possible to detect HAPA and inorganic arsenic and in the long term, Cortinas et al (2006) and Zhanga et al (2014) reported the HAPA is completely transformed into As(III) and As(V).…”

Section: Discussionmentioning

confidence: 99%

Biodegradation of roxarsone by a bacterial community of underground water and its toxic impact

Mafla

Moraga

León

et al. 2015

World J Microbiol Biotechnol

View full text Add to dashboard Cite

Roxarsone is included in chicken food as anticoccidial and mainly excreted unchanged in faeces. Microorganisms biotransform roxarsone into toxic compounds that leach and contaminate underground waters used for human consumption. This study evaluated roxarsone biotransformation by underground water microorganisms and the toxicity of the resulting compounds. Underground water from an agricultural field was used to prepare microcosms, containing 0.05 mM roxarsone, and cultured under aerobic or anaerobic conditions. Bacterial communities of microcosms were characterized by PCR-DGGE. Roxarsone degradation was measured by HPLC/HG/AAS. Toxicity was evaluated using HUVEC cells and the Toxi-ChromoTest kit. Roxarsone degradation analysis, after 15 days, showed that microcosms of underground water with nutrients degraded 90 and 83.3% of roxarsone under anaerobic and aerobic conditions, respectively. Microcosms without nutrients degraded 50 and 33.1% under anaerobic and aerobic conditions, respectively. Microcosms including nutrients showed more roxarsone conversion into toxic inorganic arsenic species. DGGE analyses showed the presence of Proteobacteria, Firmicutes, Actinobacteria, Planctomycetes and Spirochaetes. Toxicity assays showed that roxarsone biotransformation by underground water microorganisms in all microcosms generated degradation products toxic for eukaryotic and prokaryotic cells. Furthermore, toxicity increased when roxarsone leached though a soil column and was further transformed by the bacterial community present in underground water. Therefore, using underground water from areas where roxarsone containing manure is used as fertilizer might be a health risk.

show abstract

“…Zhang et al (2014) showed biodegradation of ROX in anaerobic granular sludge, reporting rapid biodegradation of ROX, followed by production and then degradation of HAPA. Zhang et al (2014) also measured distribution of ROX and its metabolites between the liquid phase and the sludge, after 240 days of incubation, indicating that 11.4%e56.7% of the total As added was in the sludge and not in the liquid phase, depending on initial As concentration. Degradation of ROX and HAPA was also observed even on much shorter time scales, after 24 h. O'Day et al (2004) explained that in reducing zones of aquifers, the association of arsenic with sulfide may occur, depending on e soil, aerobic, Â -sand, aerobic, e soil at strong chemically-induced reducing (SCIR), e sand at SCIR and bromide e sand, aerobic, and (B) from As 3þ e sand, aerobic, e soil at SCIR, e soil, aerobic, as a function of pore volume, in saturated soil and sand.…”

Section: Rox Transport Under Various Redox Conditionsmentioning

confidence: 97%

“…The iAs(V) molecule is reduced, probably biologically, to iAs(III) under anaerobic conditions (O'Day et al, 2004). Zhang et al (2014) showed biodegradation of ROX in anaerobic granular sludge, reporting rapid biodegradation of ROX, followed by production and then degradation of HAPA. Zhang et al (2014) also measured distribution of ROX and its metabolites between the liquid phase and the sludge, after 240 days of incubation, indicating that 11.4%e56.7% of the total As added was in the sludge and not in the liquid phase, depending on initial As concentration.…”

Section: Rox Transport Under Various Redox Conditionsmentioning

confidence: 99%

Transport of gadolinium- and arsenic-based pharmaceuticals in saturated soil under various redox conditions

2016

View full text Add to dashboard Cite

Biodegradation and speciation of roxarsone in an anaerobic granular sludge system and its impacts

Cited by 58 publications

References 32 publications

Precipitation of organic arsenic compounds and their degradation products during struvite formation

Precipitation of organic arsenic compounds and their degradation products during struvite formation

Biodegradation of roxarsone by a bacterial community of underground water and its toxic impact

Transport of gadolinium- and arsenic-based pharmaceuticals in saturated soil under various redox conditions

Contact Info

Product

Resources

About