Biodegradation of bezafibrate by the activated sludge under aerobic condition: Effect of initial concentration, temperature and pH

Sui, Qian; Yan, Pingping; Cao, Xuqi; Zhao, Wentao; Chen, Maozhe

doi:10.1016/j.emcon.2016.09.001

Cited by 13 publications

(4 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This phenomenon could impact the RBT results in a way that the inocula in the test are transferred from their native environment to a batch culture with different physico-chemical conditions, possibly leading to a modification in catabolic gene expression. For example, the incubation temperature has been shown to influence the biodegradation rate of several organic compounds, (Lotto, Calil, Guedes, & Rosa, 2004;Sui et al, 2016). Moreover, even if the test conditions are the same, two supposedly identical inocula may have different responses due to phenotypic heterogeneity between them (Ackermann, 2015).…”

Section: Phenotypic Adaptationmentioning

confidence: 99%

Implications of microbial adaptation for the assessment of environmental persistence of chemicals

Poursat

Spanning

Voogt

et al. 2019

Critical Reviews in Environmental Science and Technology

104

View full text Add to dashboard Cite

Persistency of organic chemicals is a key property in their environmental risk assessment. Information on persistency is often derived from the results of biodegradability screening tests such as the ready biodegradability tests (RBTs). RBTs are, however, not designed for this purpose and suffer from several problems that lead to a high variability of the results and, hence, to difficulties in their interpretation. The origin and exposure history of the inocula used for biodegradability testing can lead to highly variable outcomes. Microbial adaptation to chemicals and its impact on biodegradation needs further investigation in order to have a better understanding of their effects on persistency assessments of chemicals. It is well described that microbial adaptation stimulates biodegradation of organic chemicals. Several mechanisms responsible for these phenomena have been described, amongst which are i) shifts in community composition or abundances, ii) mutations within populations, iii) horizontal gene transfer or iv) recombination events. These adaptation processes may well be mimicked under laboratory conditions, but the outcome remains difficult to predict as we lack a fundamental understanding of the adaptive responses. This review aims to bring together our current knowledge regarding microbial adaptation and its implication for the testing of biodegradation of chemicals. Abbreviations BHRBroad host range plasmid HGT

show abstract

Section: Phenotypic Adaptationmentioning

confidence: 99%

Implications of microbial adaptation for the assessment of environmental persistence of chemicals

Poursat

Spanning

Voogt

et al. 2019

Critical Reviews in Environmental Science and Technology

104

View full text Add to dashboard Cite

show abstract

“…Tadkaew et al (2010) studied the removal of several pharmaceuticals in a submerged membrane bioreactor (MBR) at different pH values (between 5 and 9) and showed a strong influence of pH in the removal of ibuprofen, ketoprofen, diclofenac and sulfamethoxazole, with the highest removals being achieved at pH 5 [153]. On the other hand, in a different study, but for the same pH range, no significant influence of pH on the removal of the anti-lipidic bezafibrate, in an activated sludge system, was observed [154]. Baena-Nogueras et al (2017) showed that pH has a key role in the photodegradation of many pharmaceutical compounds [155].…”

Section: Removal Of Pharmaceuticals In Wastewater Treatment Plants and Factors That Can Affect Their Removalmentioning

confidence: 92%

Pharmaceutical Compounds in Aquatic Environments—Occurrence, Fate and Bioremediation Prospective

Fernandes

Almeida

Salgado

et al. 2021

Toxics

View full text Add to dashboard Cite

Various contaminants of emerging concern (CECs) have been detected in different ecosystems, posing a threat to living organisms and the environment. Pharmaceuticals are among the many CECs that enter the environment through different pathways, with wastewater treatment plants being the main input of these pollutants. Several technologies for the removal of these pollutants have been developed through the years, but there is still a lack of sustainable technologies suitable for being applied in natural environments. In this regard, solutions based on natural biological processes are attractive for the recovery of contaminated environments. Bioremediation is one of these natural-based solutions and takes advantage of the capacity of microorganisms to degrade different organic pollutants. Degradation of pollutants by native microorganisms is already known to be an important detoxification mechanism that is involved in natural attenuation processes that occur in the environment. Thus, bioremediation technologies based on the selection of natural degrading bacteria seem to be a promising clean-up technology suitable for application in natural environments. In this review, an overview of the occurrence and fate of pharmaceuticals is carried out, in which bioremediation tools are explored for the removal of these pollutants from impacted environments.

show abstract

“…Outro estudo realizado por Sui., et al, (2016) demonstra que o fármaco bezafibrato um dos medicamentos muito utilizado para prevenir ataques cardíacos e tratar doenças lipídicas, pode ser detectado na superfície aquática em concentrações de até 3,1 mg/L enquanto em efluentes é 4,6 mg/L. Devido aos efeitos combinados com outros fármacos e sua toxicidade ele acaba sendo prejudicial principalmente para o ambiente aquático.…”

Section: Biorremediação De Reguladores Lipídicosunclassified

Biodegradação e biorremediação de fármacos, cosméticos e produtos de higiene pessoal

Silva,

Melo,

Uber

et al. 2022

Biodegradação E Biorremediação

View full text Add to dashboard Cite

Biodegradation of bezafibrate by the activated sludge under aerobic condition: Effect of initial concentration, temperature and pH

Cited by 13 publications

References 20 publications

Implications of microbial adaptation for the assessment of environmental persistence of chemicals

Implications of microbial adaptation for the assessment of environmental persistence of chemicals

Pharmaceutical Compounds in Aquatic Environments—Occurrence, Fate and Bioremediation Prospective

Biodegradação e biorremediação de fármacos, cosméticos e produtos de higiene pessoal

Contact Info

Product

Resources

About