Biodegradation of pharmaceutical compounds in industrial wastewater using biological treatment: a comprehensive overview

Moghaddam, Ali; Khayatan, Danial; Barzegar, Peyman Esmaeili Fard; Ranjbar, Reza; Yazdanian, Mohsen; Tahmasebi, Elahe; Alam, Mostafa; Abbasi, Kamyar; Ghaleh, H. Esmaeili Gouvarchin; Tebyanian, Hamid

doi:10.1007/s13762-023-04880-2

Cited by 30 publications

(10 citation statements)

References 169 publications

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“…At present, studies have been reported on the biodegradation of drugs in water bodies. [12][13][14] However, biodegradation reaction rates are slow, [15,16] while the use of Fenton reagent may affect the growth and degradation of microbial communities in wastewater. Singh et al have argued that hydroxy radical introduced by Fenton reagents can trigger direct DNA alterations and other genotoxic effects on cells, [48] while significantly increased the proportion of methanogenic microorganisms in the bacterial community.…”

Section: Possible Factors Affecting Drug Abatementmentioning

confidence: 99%

“…[9][10][11] Currently, studies have been reported on the biodegradation of low concentrations of illicit drugs and medicines in water bodies. [12][13][14] However, microorganisms are rarely found in natural environments, their release into natural waters may have impacts on aquatic ecosystems, and microbial degradation reaction rates are slow. [15,16] Meanwhile, photocatalytic, [17] ultrasonic catalysis, [18,19] O 3 oxidation technology [20,21] and supercritical water oxidation [22,23] have been used to degrade organic pollution in water bodies.…”

Section: Introductionmentioning

confidence: 99%

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Investigating the Removal Efficiency of Fenton Reaction for Drugs in Municipal Wastewater

Bai,

Wang,

Liu

et al. 2024

ChemistrySelect

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Drugs and their metabolites have become new types of pollutants, the presence of which constitutes a serious environmental problem. This article applies the established LC–MS/MS method to investigate the removal efficiency of different ratios of Fenton reagents for common drugs in wastewater. The results showed that the linearity of the 10 common drugs was good in the dynamic range of 1–100 ng/L, and the R2>0.99. The LODs and LOQs ranged from 0.01–0.443 ng/L and 0.04–1.44 ng/L, respectively. The average relative recoveries ranged from 72.99–117 %. In addition, considering the economic and application effects of chemical reagents, the optimal test dose of H2O2 in Fenton reagent was determined to be 12.5 mL. This experiment provides a simple, rapid and low‐cost LC–MS/MS method for the detection of drugs in wastewater. It also provides data reference for effective management of drug production sites and domestic wastewater pollution.

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Section: Possible Factors Affecting Drug Abatementmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Investigating the Removal Efficiency of Fenton Reaction for Drugs in Municipal Wastewater

Bai,

Wang,

Liu

et al. 2024

ChemistrySelect

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“…Environmental pollution is widely known as a major challenge attributed to today's civilization 1 . The industrial and pharmaceutical solid waste, hazardous waste and effluent discharges are the leading causes and agents of water pollution all over the world 2 . Pharmaceutical wastewater as consequences of a variety of production stages including conversion of natural substances into pharmaceutical ingredients through fermentation and extraction are generally characterized with toxic and refractory compounds 3 ; the improper discharge of these compounds into environment exacerbate the environmental pollution 4 .…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, the conventional wastewater treatment methods are not able to efficiently remove or degrade such refractory and toxic compounds present in pharmaceutical wastewater 8 . In addition, the increased awareness on potential threats of pharmaceutical wastewater make researchers to employ different treatment technologies including activated carbon filter and coagulation, biological treatments, advanced oxidation processes and combined advanced oxidation processes (AOPs) and biological treatment 2 , 9 in order to meet standards recommended for discharge into environment. For instance, Changotra et al (2019) investigated the treatment of pharmaceutical wastewater using combined approach of Fenton applications and aerobic biological treatment 10 .…”

Section: Introductionmentioning

confidence: 99%

A comparative study on performance of the conventional and fixed-bed membrane bioreactors for treatment of Naproxen from pharmaceutical wastewater

Mokhtariazar,

Hassani,

Borghei

et al. 2024

Sci Rep

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Here, a comparative study was designed to survey the treatment efficiency of pharmaceutical wastewater containing Naproxen by Membrane bioreactor (MBR) and MBR with fixed-bed packing media (FBMBR). To this end, the performance of MBR and FBMBR in different aeration conditions including average DO (1.9–3.8 mg/L), different organic loading (OLR) (0.86, 1.14 and 1.92 kg COD per cubic meter per day), and Naproxen removal efficiency. The BOD5 removal efficiency, effluent quality and membrane fouling were monitored within 140 days. The results obtained from the present study indicated that COD removal efficiency for FBMBR (96.46%) was higher than that for MBR (95.33%). In addition, a high COD removal efficiency was experienced in both MBR and FBMBR in operational conditions 3 and 4, even where OLR increased from 1.14 to 1.92 kgCOD/m3 d and DO decreased from 4 to < 1 mg/L. Furthermore, the higher Naproxen removal efficiency was observed in FBMBR (94.17%) compared to that for MBR (92.76%). Therefore, FBMBR is a feasible and promising method for efficient treatment of pharmaceuptical wastewater with high concentrations of emerging contaminant, especially, the Naproxen.

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“…In general, there are various methods of removing pharmaceuticals from water systems, and most of them are based on biological, chemical, and physical approaches. Among the promising methods, adsorption [14][15][16], nanofiltration and nanoadsorption [17,18], membrane bioreactors [19,20], biological degradation [21,22], and advanced oxidation processes (AOPs) [23,24] have been explored and demonstrated to be successful in the removal of pharmaceuticals from aqueous solutions. Considering the respective advantages and disadvantages of each method, adsorption, biological degradation, and AOPs have attracted great attention [25].…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in Advanced Oxidation Processes for Degrading Pharmaceuticals in Wastewater—A Review

Roslan,

Lau,

Suhaimi

et al. 2024

Catalysts

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A large variety of pharmaceutical compounds have recently been detected in wastewater and natural water systems. This review highlighted the significance of removing pharmaceutical compounds, which are considered indispensable emerging contaminants, from wastewater and natural water systems. Various advanced oxidation processes (AOPs), including UV-H2O2, Fenton and photo-Fenton, ozone-based processes, photocatalysis, and physical processes, such as sonolysis, microwave, and electron beam irradiation, which are regarded as the most viable methods to eliminate different categories of pharmaceutical compounds, are discussed. All these AOPs exhibit great promising techniques, and the catalytic degradation process of the emerging contaminants, advantages, and disadvantages of each technique were deliberated. Heterogeneous photocatalysis employing metal oxides, particularly anatase TiO2 nanoparticles as catalysts activated by UV light irradiation, was reviewed in terms of the electron–hole separation, migration of the charge carriers to the catalyst surfaces, and redox potential of the charge carriers. This brief overview also emphasized that anatase TiO2 nanoparticles and TiO2-based nanomaterials are promising photocatalysts, and a combination of photocatalysis and other AOPs enhanced photocatalytic degradation efficiency. Finally, the challenges of applying anatase TiO2-based photocatalysis in environmental remediation and wastewater treatments to degrade pharmaceutical compounds, including mass spectroscopic analysis and a biological activity test of by-products of the emerging contaminants resulting from photocatalysis, are summarized.

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Biodegradation of pharmaceutical compounds in industrial wastewater using biological treatment: a comprehensive overview

Cited by 30 publications

References 169 publications

Investigating the Removal Efficiency of Fenton Reaction for Drugs in Municipal Wastewater

Investigating the Removal Efficiency of Fenton Reaction for Drugs in Municipal Wastewater

A comparative study on performance of the conventional and fixed-bed membrane bioreactors for treatment of Naproxen from pharmaceutical wastewater

Recent Advances in Advanced Oxidation Processes for Degrading Pharmaceuticals in Wastewater—A Review

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