Biodentine™ – use in dentistry. Literature review

Highlights Biodentine has undergone thorough research as a bone grafting substance due to its ability to promote bone regeneration and effectively treat root or tooth fractures. PRF and Biodentine can stimulate osteogenesis, affecting bone repair, particularly in mandibular fractures. Abstract Background: Mandibular fracture is one of the most common fractures. The most common treatment for mandibular fractures is fixation. Therefore, xenogeneic agents such as platelet-rich fibrin (PRF) and Biodentine accelerate the reparative process. Biodentine is an interesting active ingredient that can induce bone regeneration. PRF and Biodentine can promote bone healing, but no literature discusses the differences between PRF and Biodentine osteoinduction mechanisms in treating mandibular fractures. Objective: This article aimed to compare the effect of osteoinductive PRF with Biodentine for mandibular fractures. Material and Method: The research was conducted as a scoping review by performing a thorough search of the PubMed, Scopus, Science Direct, Elsevier, and Google Scholar databases. The study was obtained based on literature studies in the form of journals and textbooks in the last ten years (2013-2023). Result: The osteoinductive effect and mechanism of Biodentine in enhancing bone repair are likely correlated with releasing biologically active ions from calcium silicate cement and stimulating gene expression Runx-2. PRF has an osteoinductive role, causing the mechanism of releasing growth factors such as PDGF, VEGF, TGF-Î², and IGF that promote the osteogenic process. Conclusion: There was no significant difference in the osteoinduction effect of PRF and Biodentine because these materials have different mechanisms of action for bone repair.

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The Use of Mineral Trioxide Aggregate and Biodentine in Furcal Perforations Sealing – A Review Article

Pietrzycka

2024

Journal of Health Study and Medicine

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Pulp cavity perforation is defined as pathological connection between root canal system and external surface of the tooth. This iatrogenic pulp chamber injury may have serious implications on the success of root canal treatment. The sealing of perforation is crucial for good prognosis of the treated tooth. The ideal material for sealing perforations in the pulp cavity should be characterized by a good adhesion, lack of sensitivity to tissue fluids, volume stability, radiopacity on radiographs and excellent bioactivity and biocompatibility. To date the most well -known bioceramic material to is mineral trioxide aggregate. Due to over thirty years of its application in endodontics, it is called the „gold standard” for perforation repair. Recently, many new bioceramic materials have been developed and introduced to dentistry and endodontics, showing promising clinical results. One of the materials successfully used for pulp chamber floor perforation repair is Biodentine. According to the manufacturers, Biodentine has a much shorter setting time compared to other bioceramic cements, and also has better mechanical properties and is easier to use. The aim of the article is to analyse the available research and compare the properties of those bioceramic materials in a perforation sealing procedure. Based on the analysis of the current literature, it can be concluded that mineral trioxide aggregate is still the most proven and tested material among bioceramic materials, but Biodentine is a good alternative as it is relatively easy to manipulate but also has predictable clinical results.

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Biodentine™ – use in dentistry. Literature review

Cited by 4 publications

References 48 publications

Calcium Silicate-Based Cement (Biodentine™) as a Bioactive Material for the Long-Term Preservation of Pulp Vitality in Restorative Dentistry and Prosthodontics

Calcium Silicate-Based Cement (Biodentine™) as a Bioactive Material for the Long-Term Preservation of Pulp Vitality in Restorative Dentistry and Prosthodontics

Osteoinductive Capacity of Platelet-Rich Fibrin vs Biodentine for Mandible Fracture

The Use of Mineral Trioxide Aggregate and Biodentine in Furcal Perforations Sealing – A Review Article

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