Biodistribution and pharmacokinetic evaluation of Korean Red Ginseng components using radioisotopes in a rat model

Metabolism and drug interactions of Korean ginseng based on the pharmacokinetic properties of ginsenosides: Current status and future perspectives

“…G-Rb1 and C–K showed similar properties. The cumulative excretion ratio of urine and feces was 88.9–92.4%, and even though it was excreted within 96–168 h, the active component was detected in small amounts in all tissues and was mainly distributed in the liver except the digestive tract, confirming the pharmacokinetic properties related to the mechanism of action of red ginseng [ 46 ]. A randomized, open-label, 2-treatment, 2 × 2 crossover study has been conducted on the pharmacokinetic properties of C–K from Korean red ginseng and fermented red ginseng (CK-30) in healthy Korean subjects.…”