The convergence of advancements in biological sciences alongside rapid progress in computing, automation, and artificial intelligence is propelling a new wave of innovation with far-reaching impacts across various sectors such as health, agriculture, consumer goods, and energy. While these advancements, which encompass gene editing and biological engineering, hold immense potential, they also entail significant risks. Particularly, our improving capacity to comprehend and manipulate biology has led to recent breakthroughs, notably the substantial reduction in DNA sequencing costs and the introduction of new methods like CRISPR for gene editing and cell reprogramming. Noteworthy advancements have been made in four specific areas: understanding and altering biomolecules, engineering cells, tissues, and organs within biosystems, bridging biology and machines through biomachines, and utilizing cells or molecules like DNA for computational purposes. Each area is progressing differently, transition-