2024
DOI: 10.4252/wjsc.v16.i10.860
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Bioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development

José Mauro Granjeiro,
Priscila Grion de Miranda Borchio,
Icaro Paschoal Brito Ribeiro
et al.

Abstract: The burgeoning field of bioengineering has witnessed significant strides due to the advent of stem cell models, particularly in their application in advanced therapy medicinal products (ATMPs). In this review, we examine the multifaceted impact of these developments, emphasizing the potential of stem cell models to enhance the sophistication of ATMPs and to offer alternatives to animal testing. Stem cell-derived tissues are particularly promising because they can reshape the preclinical landscape by providing … Show more

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