Bioengineering of green-synthesized TAT peptide-functionalized silver nanoparticles for apoptotic cell-death mediated therapy of breast adenocarcinoma

Majeed, Shahnaz; Saravanan, Muthupandian; Danish, Mohammed; Zakariya, Norul Aini; Ibrahim, Mohamad Nasir Mohamad; Rizvi, Ezaz; NisaAndrabi, Sharaf un; Barabadi, Hamed; Mohanta, Yugal Kishore; Mostafavi, Ebrahim

doi:10.1016/j.talanta.2022.124026

Cited by 61 publications

(12 citation statements)

References 53 publications

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“…35,36 The peaks at 1631 and 1345 cm −1 are associated with the amide and acyl groups in the CO−NH bond, indicating successful covalent binding of 8-arm PEO onto GO. 37,38 Furthermore, the disappearance of the peak at 10°in X-ray diffraction (XRD) also suggests successful chemical grafting of 8-arm PEO onto GO (Figure S5). 39 In order to reveal the advantages of 8AP in LMBs, the physical properties of 8AP and the PP separator were compared (Figure 2).…”

Section: Resultsmentioning

confidence: 96%

“…Therefore, this coating layer would result in little loss of gravimetric and volumetric energy density. A Fourier transform infrared (FTIR) measurement was carried out to characterize the 8-arm PEO chain on the nanosheets (Figure f).The results demonstrated two new strong peaks at 2880 and 1090 cm –1 that correspond to the stretching vibrations of the C–H and C–O–C bonds, respectively. , The peaks at 1631 and 1345 cm –1 are associated with the amide and acyl groups in the CO–NH bond, indicating successful covalent binding of 8-arm PEO onto GO. , Furthermore, the disappearance of the peak at 10° in X-ray diffraction (XRD) also suggests successful chemical grafting of 8-arm PEO onto GO (Figure S5). …”

Section: Resultsmentioning

confidence: 97%

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Stabilizing Lithium Metal Batteries by Synergistic Effect of High Ionic Transfer Separator and Lithium–Boron Composite Material Anode

Naren,

Jiang,

Qing

et al. 2023

ACS Nano

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The development of lithium (Li) metal batteries (LMBs) has been limited by problems, such as severe dendrite growth, drastic interfacial reactions, and large volume change. Herein, an LMB (8AP@LiB) combining agraphene oxide-poly(ethylene oxide) (PEO) functionalized polypropylene separator (8AP) with a lithium−boron (LiB) anode is designed to overcome these problems. Raman results demonstrate that the PEO chain on 8AP can influence the Li + solvation structure in the electrolyte, resulting in Li + homogeneous diffusion and Li + deposition barrier reduction. 8AP exhibits good ionic conductivity (4.9 × 10 −4 S cm −1 ), a high Li + migration number (0.88), and a significant electrolyte uptake (293%). The 3D LiB skeleton can significantly reduce the anode volume changes and local current density during the charging/discharging process. Therefore, 8AP@LiB effectively regulates the Li + flux and promotes the uniform Li deposition without dendrites. The Li||Li symmetrical cells of 8AP@LiB exhibit a high electrochemical stability of up to 1000 h at 1 mA cm −2 and 5 mAh cm −2 . Importantly, the Li||LiFePO 4 full cells of 8AP@LiB achieve an impressive 2000 cycles at 2C, while maintaining a high-capacity retention of 86%. The synergistic effect of the functionalized separator and LiB anode might provide a direction for the development of high-performance LMBs.

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Section: Resultsmentioning

confidence: 96%

Section: Resultsmentioning

confidence: 97%

Stabilizing Lithium Metal Batteries by Synergistic Effect of High Ionic Transfer Separator and Lithium–Boron Composite Material Anode

Naren,

Jiang,

Qing

et al. 2023

ACS Nano

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“…Recently, the biofunctionalization of nanoparticles has attracted the attention of many researchers because of their biocompatibility, biodegradability, eco-friendly quality, and low cost . Biofunctionalization of nanoparticles has been achieved by using bioinspired ligands, phytochemicals, and bioresources such as plants, algae, bacteria, microorganisms, etc. , Nanomaterials are functionalized with different types of bioreceptor molecules, including antibodies, aptamers, peptides, and enzymes for biomedical applications. In addition, Table summarizes the selectivity, modification, stability, and sensing properties of three bioreceptor molecules for their suitability in different optical readout techniques.…”

Section: Nanomaterials Functionalization With Bioreceptorsmentioning

confidence: 99%

Optical Nanobiosensor-Based Point-of-Care Testing for Cardiovascular Disease Biomarkers

Vairaperumal,

Huang,

Liu

2023

ACS Appl. Bio Mater.

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Cardiovascular disease is a global health threat, and detecting cardiac biomarkers is essential for early-stage diagnosis and personalized treatment. Traditional approaches have limitations, but optical nanobiosensors offer rapid, highly selective, and sensitive detection. Optical nanobiosensors generate biosignals that transfer light signals while analytes bind with the bioreceptors. Optical nanobiosensors have advantages such as ease of monitoring, low cost, a wide detection range, and high sensitivity without any interference. An optical nanobiosensor platform is a promising approach for point-of-care cardiac biomarker detection with a low detection limit. This review mainly focuses on the detection of cardiovascular disease biomarkers based on various optical nanobiosensor approaches that have been reported during the last five years, and we have categorized them based on optical signal readouts. A detailed discussion of the classification of cardiovascular disease biomarkers, design strategies of optical biosensors, types of optically active nanomaterials, types of bioreceptors, functionalization techniques, various assay types, and sensing mechanisms is presented. Then, we summarize the optical signaling readout-based various nanobiosensors systems for the detection of cardiovascular disease biomarkers. Finally, we summarize and conclude with the recent development of point-of-care testing (PoCT) for cardiovascular disease biomarkers used in various optical readout techniques.

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“…Other assistance includes high yield, controlled particle size and shape, low cost, high stability of the particles, better quality, higher water solubility, and it is ecofriendly and pollution free. Silver nanoparticles (AgNPs) which are synthesised from plants have enormous supremacy in the field of medicine [7]. Use of novel plants like S. anacardium, G. lanceolarium, and B. retusa was found beneficial in commercial production of AgNPs which showed strong antibacterial and anti-biofilm activity against different clinically important human pathogens [8].…”

Section: Introductionmentioning

confidence: 99%

Grewia tenax bark extract mediated silver nanoparticles as an antibacterial, antibiofilm and antifungal agent

Yadav,

Jain,

Nimesh

et al. 2024

Adv. Nat. Sci: Nanosci. Nanotechnol.

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Grewia tenax plant possesses many medicinal qualities that can be harnessed for bio-applications via nanotechnology in a cost-effective and environment-friendly manner. The synthesised silver nanoparticles (GTB-AgNPs) from Grewia tenax bark extract were first detected by observing the change in colour from yellowish brown to dark brown and confirmed by UV–vis spectroscopy. UV–vis spectral analysis recorded the surface plasmon resonance at 420 nm. In the current research, several process parameters (time, temperature, concentration of AgNO3 and the ratio of extract to AgNO3) were adjusted by using one variable at a time (OVAT) approach. Spectroscopy accompanied by dynamic light scattering (DLS), x-ray diffraction (XRD) and scanning electron microscopy (SEM) with energy dispersive x-ray (EDX) determines the size, nature, morphological variations and chemical constituents of GTB-AgNPs. The size range was found within 35−45 nm and the image clearly showed that the GTB-AgNPs were spherical in shape and well dispersed in nature. Zeta potential and Fourier-transform infrared spectroscopy (FTIR) were done to analyse GTB-AgNPs stability, dispersion and the biomolecules in aqueous bark extract liable for the bioreduction of silver particles. These GTB-AgNPs showed excellent antibacterial action against Gram-positive (S. aureus and B. subtilis) and Gram-negative bacteria (P. aeruginosa and E. coli) which was observed by disc diffusion assay. Congo red agar plate (CRA) assay effectively unveiled the antibiofilm proficiency of the particles. These studies displayed a reduction in bacterial sustainability and the formation of exopolysaccharides. Disc diffusion assay confirmed the antifungal competency against A. niger and C. albicans. SEM was performed to elucidate the intracellular breakage and morphological transformations in cells of Gram-positive bacteria and fungi after treatment with GTB-AgNPs. The current study, therefore, enlightened applications of GTB-AgNPs as an efficient antimicrobial agent and applicable substitute in the pharmaceutical area.

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Bioengineering of green-synthesized TAT peptide-functionalized silver nanoparticles for apoptotic cell-death mediated therapy of breast adenocarcinoma

Cited by 61 publications

References 53 publications

Stabilizing Lithium Metal Batteries by Synergistic Effect of High Ionic Transfer Separator and Lithium–Boron Composite Material Anode

Stabilizing Lithium Metal Batteries by Synergistic Effect of High Ionic Transfer Separator and Lithium–Boron Composite Material Anode

Optical Nanobiosensor-Based Point-of-Care Testing for Cardiovascular Disease Biomarkers

Grewia tenax bark extract mediated silver nanoparticles as an antibacterial, antibiofilm and antifungal agent

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