Biofabrication of Nanoparticles in Wound‐Healing Materials

Khan, Nishat; Arora, Isha; Chandra, Amrish; Garg, Seema

doi:10.1002/9781119900931.ch10

Green Synthesis of Nanomaterials 2024

DOI: 10.1002/9781119900931.ch10

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Biofabrication of Nanoparticles in Wound‐Healing Materials

Nishat Khan,

Isha Arora,

Amrish Chandra

et al.

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2024

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Cited by 2 publications

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Green synthesis of magnesium oxide nanoparticles using the extract of Falcaria vulgaris to enhance the healing of burn wounds

Khazaei,

Meskaraf-asadabadi,

Khazaei

et al. 2024

Journal of Drug Targeting

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Green synthesis of magnesium oxide nanoparticles using the extract of Falcaria vulgaris to enhance the healing of burn wounds

Khazaei,

Meskaraf-asadabadi,

Khazaei

et al. 2024

Journal of Drug Targeting

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In vitro chronic wound healing using collagen and plant extract along with zinc nanoparticles

Bobby,

Purnima,

Mythily

et al. 2024

EAI Endorsed Trans Perv Health Tech

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INTRODUCTION: While the use of zinc nanoparticles (ZnNPs) as an antibacterial agent in the biomedical industry has recently attracted significant attention, collagen has aroused significant interest as a biomaterial in medical and tissue engineering applications. OBJECTIVES: In order to create biofilm loaded with biosynthesized ZnNPs for use in chronic wound healing applications, type-I collagen was extracted from the study's subject. by the acid soluble collagen technique, collagen was isolated from the fish skin of the trevally and identified by SDS-PAGE. Aqueous extract from Cassia fistula leaves was also used to greenly manufacture stable ZnNPs, which were then characterized by UV-Vis, FTIR, and XRD measurements. METHODS: Collagen and ZnNPs were then added to polyvinyl alcohol (PVA), creating a thin biofilm that had a high biocompatibility due to the production method's absence of a chemical reducer and crosslinking agent. When tested against the harmful bacteria, both ZnNPs alone and PVA/Collagen/ZnNPs biofilms showed potent antibacterial activity. RESULTS: By using the MTT test, the cytotoxic effects of collagen and ZnNPs on the Vero cell line were evaluated. With 97.76% wound closure, the PVA/Collagen/ZnNPs biofilm demonstrated strong in vitro wound scratch healing efficacy. CONCLUSION: The findings show that the PVA/Collagen/ZnNPs film dramatically increased cell migration by 40.0% at 24 hours, 79.20% at 48 hours, and 97.76% at 74 hours.

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Biofabrication of Nanoparticles in Wound‐Healing Materials

Cited by 2 publications

References 21 publications

Green synthesis of magnesium oxide nanoparticles using the extract of Falcaria vulgaris to enhance the healing of burn wounds

Green synthesis of magnesium oxide nanoparticles using the extract of Falcaria vulgaris to enhance the healing of burn wounds

In vitro chronic wound healing using collagen and plant extract along with zinc nanoparticles

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