Biofilm Formation by Candida Species on Silicone Surfaces and Latex Pacifier Nipples: An in vitro Study

Abstract

The present study assessed the growth and development of biofilm formation by isolates of C. albicans, C. glabrata and C. parapsilosis on silicone and latex pacifier nipples. The silicone and latex surfaces were evaluated by scanning electronic microscopy (SEM). The plastic component of the nipple also seems to be an important factor regarding the biofilm formation by Candida spp. The biofilm growth was measured using the MTT reduction reaction. C. albicans was found to have a slightly greater capacity of forming biofilm compared to the other Candida species. Analysis of the pattern of biofilm development by C. albicans,C. glabrata and C. parapsilosis on latex and silicon pacifier shields showed an increased biofilm formation regarding the latter substrate. Silicone was shown to be more resistant to fungal colonization, particularly in the case of C. parapsilosis, despite the lack of any statistically significant differences (P > 0.05). In addition, silicone has a smoother surface compared to latex, whose surface was found to be rugose and irregular

A case of asymptomatic fungal and bacterial colonization ofan intragastric balloon

“…Colonization of soft lining materials with microorganisms, particularly Candida species, is a common clinical problem. The intragastric balloon has a silicon elastomer structure and da Silveira et al [11] mentioned in their paper that silicone-based soft lining materials are more susceptible to Candida adhesion.…”

Control of bacterial biofilms formed on pacifiers by antimicrobial solutions in spray

“…Nipples can be composed by different materials such as latex or silicone. Nowadays, the use of silicone nipples is preferred due to their lower roughness and lower microbial adhesion. As they are in direct contact with the oral microflora, microbial biofilms may grow on their surfaces.…”

“…Nowadays, the use of silicone nipples is preferred due to their lower roughness and lower microbial adhesion. As they are in direct contact with the oral microflora, microbial biofilms may grow on their surfaces. These biofilms may be a potential reservoir for pathogenic species, such as Staphylococcus and Candida .…”

Rotation Disk Process to Assess the Influence of Metals and Voltage on the Growth of Biofilm

“…They wanted to carry out a separate study to find methods of inhibiting bacteria/biofilm growth on latex, especially since it is used in catheters and other medical devices. They read and considered journal articles about latex and biofilm [8,9,10,11,12]. However, that information did not directly relate to their work, which they considered to be a new area of study.…”