Biogenic Amines and the States of Sleep

Jouvet, Michel

doi:10.1126/science.163.3862.32

Cited by 1,257 publications

(331 citation statements)

References 52 publications

Supporting

Mentioning

307

Contrasting

Unclassified

Order By: Relevance

“…Molecular genetic studies have shed light on specific genetic variants influencing the associations between sleep and emotional difficulties. For example, genes involved in the serotonin pathways are likely to play a role in the associations between sleep and anxiety given the role of serotonin with regards to each phenotype (Jouvet 1969;Lesch et al 1996). As well as identifying genetic influences, specifying environmental influences common to both phenotypes is also informative.…”

Section: Sleep and Emotional Difficulties: Links Between Sleep And Emmentioning

confidence: 99%

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Barclay

Gregory

2013

Current Topics in Behavioral Neurosciences

View full text Add to dashboard Cite

Sleep changes throughout the lifespan, with particularly salient alterations occurring during the first few years of life, as well as during the transition from childhood to adolescence. Such changes are partly the result of brain maturation; complex changes in the organisation of the circadian system; as well as changes in daily routine, environmental demands and responsibilities.Despite the automaticity of sleep, given that it is governed by a host of complex mechanisms, there are times when sleep becomes disturbed. Sleep disturbances in childhood are common and may stem from behavioural difficulties or abnormalities in physiological processes and, in some cases manifest into diagnosable sleep disorders. As well as occurring exclusively, childhood sleep disturbances often co--occur with other difficulties. The purpose of this chapter is to outline the neurobiology of typical sleep/wake processes, and describe changes in sleep physiology and architecture from birth to adulthood. Furthermore, common childhood sleep disorders are described as are their associations with other traits, including all of the syndromes presented in this handbook: ASDs, ADHD, schizophrenia, and emotional/ behavioural difficulties. Throughout, we attempt to explain possible mechanisms underlying these disorders and their associations.

show abstract

Section: Sleep and Emotional Difficulties: Links Between Sleep And Emmentioning

confidence: 99%

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Barclay

Gregory

2013

Current Topics in Behavioral Neurosciences

View full text Add to dashboard Cite

show abstract

“…HIPPOCAMPAL THETA RHYTHMS-The most prominent oscillation in the mammalian brain is the hippocampal theta rhythm (6-12 Hz) (Green and Arduni, 1954) that is present mainly during locomotion and other 'voluntary' movements (Vanderwolf, 1969) and REM sleep (Jouvet, 1969). A crucial structure involved in theta oscillations is the medial septum-diagonal band of Broca (MSDB), because its lesion or disconnection from the hippocampus abolishes theta (Green and Arduni, 1954;Petsche et al, 1962).…”

Section: Slow (<1 Hz) Rhythms-mirceamentioning

confidence: 99%

Interaction between neocortical and hippocampal networks via slow oscillations

Sirota

Buzsáki

2005

THL

236

219

View full text Add to dashboard Cite

Both the thalamocortical and limbic systems generate a variety of brain state-dependent rhythms but the relationship between the oscillatory families is not well understood. Transfer of information across structures can be controlled by the offset oscillations. We suggest that slow oscillation of the neocortex, which was discovered by Mircea Steriade, temporally coordinates the self-organized oscillations in the neocortex, entorhinal cortex, subiculum and hippocampus. Transient coupling between rhythms can guide bidirectional information transfer among these structures and might serve to consolidate memory traces.

show abstract

“…The monoamines including serotonin (5-HT), dopamine (DA), histamine (HA), and norepinephrine (NE) were among the first compounds to have been suggested to play a role in sleep regulation (Jouvet, 1969). Their involvement has been supported in part by the development of pharmacologic agents that simultaneously modulate both the activities of these systems and vigilance states (reviewed in Jones, 1994).…”

Section: Reverse Geneticsmentioning

confidence: 99%

Perchance to dream: Solving the mystery of sleep through genetic analysis

Shaw

Franken

2002

J. Neurobiol.

View full text Add to dashboard Cite

Sleep has been identified in all mammals and nonmammalian vertebrates that have been critically evaluated. In addition, sleep-like states have also been identified and described in several invertebrates. Despite this prevalence throughout the animal kingdom, the function of sleep remains a mystery. The completion of several genome sequencing projects has led to the expectation that fundamental aspects of sleep can be elucidated through genetic dissection. Indeed, studies in both the mouse and fly have begun to reveal tantalizing suggestions about the underlying principles that regulate sleep homeostasis. In this article we will review recent studies that have used genetic techniques to evaluate sleep in the fruit fly and the mouse.

show abstract

Biogenic Amines and the States of Sleep

Cited by 1,257 publications

References 52 publications

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Sleep in Childhood and Adolescence: Age-Specific Sleep Characteristics, Common Sleep Disturbances and Associated Difficulties

Interaction between neocortical and hippocampal networks via slow oscillations

Perchance to dream: Solving the mystery of sleep through genetic analysis

Contact Info

Product

Resources

About