BioGlue and Dermabond save time, leak less, and are not mechanically inferior to two-layer and modified one-layer vasovasostomy

Saunders, Marnie M.; Baxter, Z. Chad; Abou-Elella, Ashraf A.; Kunselman, Allen R.; Trussell, J. C.

doi:10.1016/j.fertnstert.2007.12.006

Cited by 29 publications

(16 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Polyethylene glycol hydrogel agent is useful for bleeding suture of nonruptured aneurysms, preventing pericardial adhesions and treating pancreatic stumps or open wounds [52]. Because of its swelling property, polyethylene glycol hydrogel should not be used to the site where surrounding anatomic structures can be harmed by compression, instead, it could be a greatly effective hemostat for vascular, pulmonary and cardiac surgery in which extension is not an important problem [53]. Also this glue is not exothermic, does not have an inflammatory effect, and has no potential for bacterial infection.…”

Section: ) Cyanoacrylates (Dermabond®)mentioning

confidence: 99%

Era of Bloodless Surgery: Spotlights on Hemostasic Materials and Techniques

Park

Koh

2018

Hanyang Med Rev

View full text Add to dashboard Cite

Section: ) Cyanoacrylates (Dermabond®)mentioning

confidence: 99%

Era of Bloodless Surgery: Spotlights on Hemostasic Materials and Techniques

Park

Koh

2018

Hanyang Med Rev

View full text Add to dashboard Cite

“…In addition, their compositions, structures, and physical properties can be tailored for specific applications. Among synthetic tissue adhesives, cyanoacrylates have been widely used for external applications such as closure of skin wounds due to their fast curing, strong adhesion to tissues, and ease of use [52]. The synthetic adhesives based on cyanoacrylate are liquid monomers.…”

Section: Conventional Surgical Materialsmentioning

confidence: 99%

“…Other commercially available cyanoacrylate-based bioadhesives are Trufill n-BCA (Cordis Neurovascular, Inc.), a combination of tantalum powder and n-butyl cyanoacrylate, and Glubran2 (GEM s.r.l. ), a modified form of n-butyl-2-cyanoacrylate [52, 54]. These products have shown strong adhesive and hemostatic properties for various clinical applications, but they can only be employed for external use due to their potential toxicity and pro-inflammatory characteristic upon contacting non-cutaneous surfaces [55].…”

Section: Conventional Surgical Materialsmentioning

confidence: 99%

Surgical materials: Current challenges and nano-enabled solutions

et al. 2014

View full text Add to dashboard Cite

Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many clinical applications. Nano-enabled materials containing nanoparticles or having a distinct nanotopography have been utilized for generation of a new class of surgical materials with enhanced functionality. In this review, the state of the art in the development of conventional surgical adhesive biomaterials is critically reviewed and their shortcomings are outlined. Recent advancements in generation of nano-enabled surgical materials with their potential future applications are discussed. This review will open new avenues for the innovative development of the next generation of tissue adhesives, hemostats, and sealants with enhanced functionality for various surgical applications.

show abstract

“…The major limitations of the PEG-PEG sealant are its high degree of swell and its relatively weak adhesion to tissue. On anastomotic closures, both cyanoacrylate glue and albumin-glutaraldehyde glue demonstrate greater mechanical integrity than the PEG-PEG sealant and are capable of resisting higher loads before failure [72]. On the cut tissue surface of the kidney, fibrin sealant adheres more effectively than PEG-PEG sealant [73].…”

Section: Hydrogels For Wound Dressings and Wound Closurementioning

confidence: 99%

Hydrogel Materials

Holowka

Bhatia

2014

Drug Delivery

View full text Add to dashboard Cite

In Chap. 2, we discussed the fundamental behavior behind the release of drug molecules from matrix species in response to degradation (i.e., chemical or enzymatic), erosion (i.e., surface or bulk), and swelling (i.e., crosslinks). In the case of swellable systems, we limited our focus only to the adjustment of swelling characteristics based on changing the crosslink density, polymer molecular weight between crosslinks, and hydrophilicity. These underlying features provide information regarding the pharmacokinetics of the system; however, they provide little indication of the physical requirements for actual therapeutic applications. For example, what if a swellable system reached a point within the human body where the matrix could not sustain its own structural integrity? What would be the consequences of the system breaking apart? Could we see premature drug release [1], an inflammatory response [2], or perhaps worse, the occlusion of an artery [3]? When we use swellable systems in physiological environments, care must be taken to understand the properties, both chemical and physical, to which it will be exposed throughout its life cycle within the body.In this chapter, we will discuss aqueous swellable systems classified as hydrogels [4], and their applications as implantable [5] and injectable [6] systems. Hydrogels are a species of crosslinked, hydrophilic, polymer molecules that absorb large amounts of water (≤99 %) to form a three-dimensional network. There is a broad application base for hydrogel materials, ranging from tissue engineering scaffolds [7] to breast implants [8] to contact lenses [9] (discussed in Chap. 2, Sect. 2.3). For the purposes of our current discussion, we will focus on implantable biosensors for diabetes treatment [10] and injectable hydrogels for cartilage repair [11]. We begin

show abstract

BioGlue and Dermabond save time, leak less, and are not mechanically inferior to two-layer and modified one-layer vasovasostomy

Cited by 29 publications

References 18 publications

Era of Bloodless Surgery: Spotlights on Hemostasic Materials and Techniques

Era of Bloodless Surgery: Spotlights on Hemostasic Materials and Techniques

Surgical materials: Current challenges and nano-enabled solutions

Hydrogel Materials

Contact Info

Product

Resources

About