Bioherbicidal Effects of Essential Oils Isolated from Thymus fallax F., Mentha dumetorum Schult. and Origanum vulgare L.

Yılar, Melih; Bayan, Yusuf; Akşit, Hüseyin; Onaran, Abdurrahman; Kadıoğlu, İzzet; Yanar, Yusuf

doi:10.14233/ajchem.2013.14109

Cited by 10 publications

(8 citation statements)

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“…These results were almost similar to other studies in Iran which were characterized by a high content of thymol (61.14-79.74%) [24][25][26]. In another investigation in Turkey, thymol with a lesser amount in comparison with the current study (41.48%) was the main constituent of the oil [27]. On the other hand, some other investigations in both Turkey and Iran showed that carvacrol was the principal component (66.1-69.2%) and thymol amounts were much lower in comparison with our results [17,28,29].…”

Section: Discussionsupporting

confidence: 92%

Antimicrobial and Anti‐Biofilm Activities of Thymus fallax Essential Oil against Oral Pathogens

Moshaverinia

Sahmeddini

Lavee

et al. 2022

BioMed Research International

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Aim. Oral infections associated with a wide diversity of microorganisms, including bacteria and yeasts, occur frequently in humans, affecting the whole oral cavity and well-being. Oral pathogens easily grow and propagate in the oral cavity, leading to the formation of dental plaque on both soft and hard tissue. The oral cavity contains up to 700 different species of microorganisms, which Candida and Streptococci are the most common organisms. Oral diseases continue to increase despite the best efforts of the medical and scientific communities. During the past decades, drug resistance to common antibiotics used in the treatment of oral infections has been raised to high levels worldwide. To overcome such resistance, there is a growing tendency to use herbal medicine as alternative. This study was conducted to find out the chemical constitution of Thymus fallax (T. fallax) essential oil and to determine its antimicrobial and anti-biofilm efficacy against common oral pathogens. Materials and Methods. The chemical compositions of the essential oil distilled from T. fallax plants were analyzed using gas chromatography/mass spectrometry (GC/MS). Antimicrobial susceptibility testing against common Streptococcus, Enterococcus, Staphylococcus, and Candida strains was assessed by broth microdilution in 96-well plates as suggested by the Clinical and Laboratory Standards Institute (CLSI) methods. Biofilm growth and development were assessed using XTT reduction assay. Results. Based on the GC/MS test results, thymol (67.75%) followed by caryophyllene (E-) (7.27%) was the main component of this essential oil. T. fallax inhibited the growth of examined microbial pathogens at concentrations of 0.031-16 μL/mL. Also, the essential oil showed biofilm inhibition of greater than 95% in the concentration of 8 μL/mL against all tested bacterial strains as well as Candida albicans ( p value < 0.05). Conclusions. Considering the significant antimicrobial activities of T. fallax, this essential oil has the potential to be used as further antimicrobial and anti-biofilm pharmaceutical products in the control and treatment of oral infections.

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Section: Discussionsupporting

confidence: 92%

Antimicrobial and Anti‐Biofilm Activities of Thymus fallax Essential Oil against Oral Pathogens

Moshaverinia

Sahmeddini

Lavee

et al. 2022

BioMed Research International

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“…Several authors have shown that essential oils rich in phenolic compounds (thymol is a phenolic compound) possess interesting inhibitory effects on seed germination and the radical and seedling growth of several plants [ 15 , 16 , 17 ]. These essential oils may also induce oxidative stress during seed germination and seedling growth.…”

Section: Resultsmentioning

confidence: 99%

The Essential Oil of Monarda didyma L. (Lamiaceae) Exerts Phytotoxic Activity in Vitro against Various Weed Seed

2017

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The chemical composition of the essential oil of the flowering aerial parts of Monarda didyma L. cultivated in central Italy was analyzed by Gas Chromatography/Mass Spectrometry (GC/MS). The major compounds of the oil were thymol (59.3%), p-cymene (10.3%), terpinolene (9.2%), δ-3-carene (4.4%), myrcene (3.7%), and camphene (3.4%). The essential oil was tested in vitro for its anti-germination activity against Papaver rhoeas L., Taraxacum officinale F. H. Wigg., Avena fatua L., Raphanus sativus L. and Lepidium sativum L. seeds, demonstrating good inhibitory activity in a dose-dependent way. The exposure of the employed weed seeds to M. didyma essential oil and thymol solution (59.3%) increased the level of hydrogen peroxide (H2O2) and malondialdehyde (MDA), markers of oxidative stress, in emerging 5-day-old rootlets.

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“…The bioherbicidal effects of O. vulgare EO could be also due to its composition of phenolic compounds such as thymol and carvacrol [ 38 ]. Furthermore, oregano EO was able to inhibit significantly the seeds germination and the roots and shoots growth of Avena sterilis L., Datura stramonium L., Cucumis sativus L. and Lactuca sativa L. [ 38 ]. Further research demonstrated that several plant EOs and their phenolic compounds, carvacrol, and thymol, have herbicidal effects on weed germination and seedling growth of various plant species.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxic Activity of Origanum Vulgare L. on Hepatocellular Carcinoma cell Line HepG2 and Evaluation of its Biological Activity

et al. 2017

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The potential of plant essential oils (EOs) in anticancer treatment has recently received many research efforts to overcome the development of multidrug resistance and their negative side effects. The aims of the current research are to study (i) the cytotoxic effect of the crude EO extracted from Origanum vulgare subsp hirtum and its main constituents (carvacrol, thymol, citral and limonene) on hepatocarcinoma HepG2 and healthy human renal cells HEK293; (ii) the antibacterial and phytotoxic activities of the above EO and its main constituents. Results showed that cell viability percentage of treated HepG2 by EO and its main constituents was significantly decreased when compared to untreated cells. The calculated inhibition concentration (IC50) values for HepG2 were lower than healthy renal cells, indicating the sort of selectivity of the studied substances. Citral is not potentially recommended as an anticancer therapeutic agent, since there are no significant differences between IC50 values against both tested cell lines. Results showed also that oregano EO and its main constituents have a significant antibacterial activity and a moderate phytotoxic effect. The current research verified that oregano EO and its main constituents could be potentially utilized as anticancer therapeutic agents.

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Bioherbicidal Effects of Essential Oils Isolated from Thymus fallax F., Mentha dumetorum Schult. and Origanum vulgare L.

Cited by 10 publications

References 0 publications

Antimicrobial and Anti‐Biofilm Activities of Thymus fallax Essential Oil against Oral Pathogens

Antimicrobial and Anti‐Biofilm Activities of Thymus fallax Essential Oil against Oral Pathogens

The Essential Oil of Monarda didyma L. (Lamiaceae) Exerts Phytotoxic Activity in Vitro against Various Weed Seed

Cytotoxic Activity of Origanum Vulgare L. on Hepatocellular Carcinoma cell Line HepG2 and Evaluation of its Biological Activity

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