Bioimpedance vector analysis as a measure of muscle function

Norman, Kristina; Pirlich, Matthias; Sorensen, Janice; Christensen, Peter O.; Kemps, Martin; Schütz, Tatjana; Lochs, Herbert; Kondrup, Jens

doi:10.1016/j.clnu.2008.11.001

Cited by 82 publications

(80 citation statements)

References 33 publications

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“…In agreement with this finding, we showed earlier that both resistance and reactance are predictors of muscle strength (28), and in this study population phase angle correlated with handgrip strength ( Figure 1) and peak expiratory flow, functional components of the EORTC quality-of-life questionnaire and the Karnofsky Performance Scale (data not shown).…”

Section: Discussionsupporting

confidence: 76%

Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer

Norman

Stobäus

Zocher

et al. 2010

The American Journal of Clinical Nutrition

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Background: The bioelectrical phase angle has shown predictive potential in various diseases, but general cutoffs are lacking in the clinical setting. Objectives: This study evaluated the prognostic value of the fifth percentile of sex-, age-, and body mass index-stratified phase angle reference values in patients with cancer with respect to nutritional and functional status, quality of life, and 6-mo mortality. In a second step, we also studied the effect of the standardized phase angle (with a z score to determine individual deviations from the population average) on these variables. Design: A total of 399 patients with cancer were studied. Phase angle was obtained with bioelectrical impedance analysis; muscle function was assessed by handgrip strength and peak expiratory flow. Quality of life was determined by the European Organization for Research and Treatment of Cancer questionnaire. Nutritional status was assessed by using Subjective Global Assessment. Survival of patients was documented after 6 mo. Results: Patients with a phase angle of less than the fifth reference percentile had significantly lower nutritional and functional status, impaired quality of life (P , 0.0001), and increased mortality (P , 0.001). The standardized phase angle emerged as a significant predictor for malnutrition and impaired functional status in generalized linear model regression analyses. It was also a stronger indicator of 6-mo survival than were malnutrition and disease severity in the Cox regression model (P , 0.0001) and according to the receiver operating characteristic curve. Conclusions: The standardized phase angle is an independent predictor for impaired nutritional and functional status and survival. The fifth phase angle reference percentile is a simple and prognostically relevant cutoff for detection of patients with cancer at risk for these factors.Am J Clin Nutr 2010;92:612-9.

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Section: Discussionsupporting

confidence: 76%

Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer

Norman

Stobäus

Zocher

et al. 2010

The American Journal of Clinical Nutrition

Self Cite

303

264

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“…In recent studies [8][9][10] , electrical bioimpedance (BIA) and its vectors in particular has been proposed for body composition analysis of patients with chronic liver disease 11 .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of nutritional indicators and body composition in patients with advanced liver disease enrolled for liver transplantation

2013

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PURPOSE: Malnutrition is prevalent in patients with advanced liver disease (LD) related to multifactorial causes. Fluid retention can underestimate the nutritional status based on anthropometric measures. We evaluated nutritional indicators and body composition (BC) in patients with liver cirrhosis and correlated them with LD severity. METHODS:Forty three patients with LD enrolled for liver transplantation were evaluated by Anthropometric measures, subjective evaluation (Global Assessment of Nutritional Status -SGA) and biochemical indicators. Single-frequency electrical bioimpedance (SFE-BIA) was used to evaluate body composition (BC). It measured resistance (R), reactance (Xc) and the phase angle (PA). LD severity was estimated by Child-Pugh and Meld criteria (Model for End-Stage Liver Disease). RESULTS:Child-Pugh index between patients was 7.11±1.70 and Meld was 12.23±4.22. Arm Circumference, Arm Muscle Circumference and Arm Muscle Area, SGA, hemoglobin, hematocrit and albumin showed better correlation with disease severity. Xc and PA showed correlation both with Meld and Child-Pugh score when BC were evaluated. PA was depleted in 55.8% of the patients. CONCLUSIONS:Diagnosis of malnutrition varied according to the method. Global assessment of nutritional status showed better correlation with disease severity than with objective methods. Single-frequency electrical bioimpedance for body composition analysis in cirrhotic patients must be cautiously used; however, primary vectors seems to be valid and promising in clinical practice.

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“…According to the strong relationship between measured resistance, fat-free mass (FFM), and total body water, prediction equations were developed to estimate percentage of body fat and FFM, which could be directly displayed after BIA measurement. The FFM index (FFMI) was calculated as FFM divided by body height squared (kg/m 2 ) (30,31).…”

Section: Body Compositionmentioning

confidence: 99%

Disability and Its Influence in Nutritional Assessment Tools in Elderly People Living in Nursing Homes

et al. 2017

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ResumenIntroducción: un estado nutricional deficiente está asociado con un incremento de la morbilidad y la mortalidad, especialmente en personas ancianas. Objetivo: el objetivo de este estudio fue evaluar el estado nutricional en ancianos institucionalizados en residencias geriátricas mediante diferentes test nutricionales, y determinar qué parámetros utilizados en la valoración nutricional pueden ser realizados en esta población. Métodos: se llevó a cabo un estudio transversal en 383 ancianos. Las herramientas de valoración nutricional empleadas fueron el Mini Nutritional Assessment (MNA), el nuevo consenso de definición de malnutrición, y el CONUT. Además, la capacidad de realizar las actividades básicas de la vida diaria fue evaluada con el índice de Barthel. Resultados: según el índice de Barthel, hasta un 78,9% de los residentes tenía una dependencia total, y en solo el 20,9% se pudo determinar el peso y la talla. La prevalencia de malnutrición con MNA, el consenso de ESPEN y CONUT fueron 21,3%, 17,2% y 20,7%, respectivamente. La concordancia (kappa) entre el MNA y el ESPEN fue moderada (κ = 0,483), pero con CONUT fue baja. Conclusiones: en las residencias geriátricas públicas existe un elevado porcentaje de ancianos totalmente dependientes. Este alto grado de dependencia funcional dificulta la obtención de algunos parámetros antropométricos como el peso y la talla, que son esenciales para llevar a cabo la mayoría de los test de valoración nutricional. El MNA, el CONUT y los nuevos criterios de desnutrición de la ESPEN mostraron una elevada prevalencia de desnutrición y de riesgo de desnutrición en esta población de ancianos institucionalizados, en aquellos en los que fue posible realizarlos. AbstractIntroduction: Poor nutritional status is associated with increased morbidity and mortality, especially in older people. Objective: The aim of this study was to assess nutritional status in elderly nursing home residents with different nutritional test, and to determine which parameters used for nutritional assessment can be carried out in this population, which usually have a high prevalence of functionally dependent residents. Methods: A cross-sectional study was performed in 383 elderly. The nutritional assessment tools used were the Mini Nutritional Assessment (MNA), the new ESPEN consensus definition of malnutrition, and the tool for Controlling Nutritional Status (CONUT). Moreover, the ability to perform basic activities of daily living was assessed with the Barthel index (BI). Results: According to BI, 78.9% had a total dependence and only 20.9% could be weighed and heighed. The prevalence of malnutrition with MNA, ESPEN and CONUT was 21.3%, 17.6% and 20.7%, respectively. The agreement between MNA vs ESPEN criteria was moderate (κ = 0.483), but with CONUT was low. Conclusions: Nursing homes had a high percentage of totally dependent residents. This high degree of functional dependence made difficult to obtain some anthropometric parameters such as weight and height, which are essential to carry out most ...

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Bioimpedance vector analysis as a measure of muscle function

Cited by 82 publications

References 33 publications

Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer

Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer

Evaluation of nutritional indicators and body composition in patients with advanced liver disease enrolled for liver transplantation

Disability and Its Influence in Nutritional Assessment Tools in Elderly People Living in Nursing Homes

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