Bioinformatics analysis of key genes and potential mechanism in cadmium-induced breast cancer progression

The upregulation and transcriptional regulatory mechanisms of Extra spindle pole bodies like 1 in bladder cancer: An immunohistochemistry and high-throughput screening Evaluation

“…Increasing evidence indicates that ESPL1 participates in cell cycle signalling in breast cancer [ 32 ], endometrial cancer (UCEC) [ 33 ] and HCC [ 11 ], thus promoting the proliferation and migration of cancer cells [ 14 ]. However, in terms of BC, the potential pathways in which ESPL1 is involved still need to be better defined.…”

Integrative Co-Registration of Elemental Imaging and Histopathology for Enhanced Spatial Multimodal Analysis of Tissue Sections through TRACE

“…Additionally, copper depletion therapies have shown promise in hindering tumor migration, invasion, and metastasis (Liu et al ., 2021; Chan et al ., 2017; Ramchandani et al ., 2021; Akerfeldt et al ., 2017; Baldari et al ., 2019; Fatfat et al ., 2014; Gandin et al ., 2012; Lopez et al ., 2019; Denoyer et al ., 2015; Gupte and Mumper, 2009). This is hypothesized to occur through two primary mechanisms: firstly, by reducing tumor metabolism (Ge et al ., 2022; Finney et al ., 2009; Kozono et al ., 2018; Chellan and Sadler, 2015; Fouani et al ., 2017), and secondly, by limiting the remodeling of the collagen extracellular matrix, which is crucial for tumor movement (Naji et al ., 2019; Shi et al ., 2021; Liang et al ., 2021; Wu et al ., 2022). Furthermore, lifestyle modifications, including dietary changes and minimizing exposure, are crucial for prevention and management.…”