Bioinformatics analysis of multi-epitope peptide vaccines against Hepatitis C virus: a molecular docking study
Ashraf M. Muhammad,
Ghada M. Salum,
Mai Abd El Meguid
et al.
Abstract:Background
Hepatitis C Virus (HCV) infection is one of the causal agents of liver disease burden. Six multiple antigenic peptides were synthesized including (P315, P412, and P517) plus (P1771, P2121, and P2941) to induce humoral and cellular responses, respectively against HCV infection. Aim: This paper aimed to employ computational tools to evaluate the efficacy of each peptide individually and to determine the most effective one for better vaccine development and/or immunotherapy.
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