2021
DOI: 10.21203/rs.3.rs-265387/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Bioinformatics Analysis of Prognostic Significance of VPS72 and Correlations with Immune Infiltrates in Hepatocellular Carcinoma

Abstract: Background VPS72 is part of the EP400 and Snf2-related CBP-activator protein (SRCAP) chromatin remodeling complexes, and the prognostic value of VPS72 in hepatocellular carcinoma has not been reported. Methods we used the Oncomine, UALCAN, GEPIA, String and Timer databases to study the expression of VPS72 in hepatocellular carcinoma. Results We found the overexpression of VPS72 was markedly correlated with clinical stages and pathological grades in LIHC, higher mRNA expression of VPS72 was significantly rel… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 13 publications
(13 reference statements)
0
1
0
Order By: Relevance
“…As part of the INO80 family, they regulate histone exchange [70]. ANP32E can remove H2AFZ from the nucleosome [71], while VPS72 deposits H2AFZ during mitosis [72], and immune cell infiltration [73,74] (Figure 3) that are known to be affected in the disease. The histone chaperone SET inhibits nucleosome acetylation and regulates p53-mediated cell cycle arrest [59].…”
Section: Histone Chaperonesmentioning
confidence: 99%
“…As part of the INO80 family, they regulate histone exchange [70]. ANP32E can remove H2AFZ from the nucleosome [71], while VPS72 deposits H2AFZ during mitosis [72], and immune cell infiltration [73,74] (Figure 3) that are known to be affected in the disease. The histone chaperone SET inhibits nucleosome acetylation and regulates p53-mediated cell cycle arrest [59].…”
Section: Histone Chaperonesmentioning
confidence: 99%